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The conference saw the participation of over 500 leading doctors and experts from hospitals, assisted reproduction centers, and testing centers across the country. Representing GENTIS at the event was Mr. Do Manh Ha (CEO) along with a team of product research and development specialists.
The 11th Conference on Infertility and Assisted Reproductive Techniques featured four sessions, including 18 specialized presentations, research reports, and discussions led by top doctors and experts in the fields of reproduction and assisted reproduction in Vietnam. The discussions were lively, with many questions raised and directly addressed.
Dr. Nguyen Van Thong, Specialist level II from Hung Vuong Hospital, with the presentation “Preimplantation Genetic Testing for Microdeletions: Where Do We Stand?”
One notable presentation was by Dr. Nguyen Van Thong from Hung Vuong Hospital, titled “Preimplantation Genetic Testing for Microdeletions: Where Do We Stand?” This presentation received high praise from leading professors and experts in the field. Dr. Thong emphasized the importance of screening and diagnosing microdeletions in embryos, as these abnormalities can cause severe complications, often affecting the intellectual and motor development of children after birth. Moreover, these abnormalities cannot be detected through standard tests like karyotyping, and their occurrence does not vary with maternal age.
Therefore, preimplantation genetic testing (PGT) is considered the optimal solution for selecting genetically healthy embryos, increasing the chances of successful pregnancy through in vitro fertilization (IVF), and ensuring that children are born free from screened genetic syndromes.
Dr. Thong shared that he has utilized the PGT-Max 1 test in real clinical cases at Hung Vuong Hospital.
Dr. Thong further explained, “Preimplantation genetic testing abnormalities are classified into three groups: PGT-A, PGT-M, and PGT-SR. PGT-A is used to diagnose chromosomal aneuploidies, PGT-M is for diagnosing single-gene disorders, and PGT-SR is for detecting structural abnormalities larger than 5Mb. Currently, structural abnormalities smaller than 2-5Mb remain a gray area that we have yet to fully explore.” This highlights the need for solutions to address these uncharted areas.
In response to this need, GENTIS has developed the PGT-Max 1 test, which detects aneuploidies across all 24 chromosomes, structural chromosomal abnormalities (such as duplications and deletions) greater than 5Mb, and certain common microdeletions larger than 2Mb, including the 22q11.2 deletion (related to DiGeorge syndrome), 1p36 deletion (related to 1p36 deletion syndrome), and other common microdeletions. This application offers the highest resolution currently available in Vietnam.
To achieve this breakthrough, the GENTIS research team developed the test using high-resolution Next Generation Sequencing (NGS) technology, surpassing the resolution of standard PGT tests, and applied specialized bioinformatics software capable of detecting microdeletions as small as 2Mb—something not possible with other common PGT tests on the market.
GENTIS’s Involvement in the 11th Conference on Infertility and Assisted Reproductive Techniques
GENTIS is a pioneer in PGT testing in Vietnam, with over 10 years of experience in the field. The company follows a standardized testing process and operates a laboratory system that meets the necessary standards for PGT. GENTIS was the first unit in Vietnam to receive ISO 15189:2012 certification for PGT testing.
Additionally, GENTIS has a team of experienced research and development specialists who continuously update the latest features of PGT tests. This is essential for the future, as it will allow for the development of higher-resolution PGT tests capable of detecting more abnormalities. The ultimate goal is that every embryo transferred is the best possible one, increasing pregnancy success rates and ensuring the birth of healthy babies.
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