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            [slug] => Proactive-thalassemia-screnning-a-solution-to-help-carrier-couples-have-healthy-children
            [title] => Proactive Thalassemia Screening – A Solution to Help Carrier Couples Have Healthy Children
            [description] => Thalassemia is one of the most common and dangerous hereditary blood disorders in Vietnam today. However, thanks to the advancement of modern medicine and the support of pioneering genetic testing institutions like GENTIS, thousands of Vietnamese families have successfully had healthy children—even when one or both parents carry the disease gene.
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Thalassemia: A Silent Disease with Serious Consequences
Discussing the current situation, Professor Nguyen Dinh Tao (Chairman of the Hanoi Association for Reproductive Support) shared that approximately 13% of Vietnam's population—equivalent to over 14 million people—are carriers of the Thalassemia gene without knowing it. Each year, around 8,000 children are born with the disease in Vietnam, including 2,000 severe cases and approximately 800 newborn deaths.
Children with severe Thalassemia are dependent on hospitals, blood transfusions, and lifelong treatment. This not only impacts the child’s quality of life but also places a significant financial and emotional burden on the entire family. The estimated cost of treating a Thalassemia patient over their lifetime can reach 2 to 3 billion VND—a substantial amount for most families in Vietnam.
Early Prevention – The Key to a Healthy Generation
According to Dr. Bui Thi Phuong Hoa (Head of the Department of Scientific Research and Training – Hanoi Hospital of Andrology and Infertility), Thalassemia is no longer something to fear if detected and prevented early. With significant progress in genetic medicine, Vietnam now meets international standards in gene screening and testing. Several national programs have been implemented to screen for this condition, especially targeting individuals preparing for marriage and women in early pregnancy.
A simple complete blood count (CBC) test can help detect risk factors through indicators such as MCV and MCH. If these values are low, patients will be recommended for more advanced genetic tests, including PCR, Sanger, or, notably, next-generation sequencing (NGS)—a cutting-edge method currently applied effectively at GENTIS. As a pioneer in the field of genetic testing in Vietnam, GENTIS uses NGS to minimize missed mutations and deliver high accuracy and safety for patients.
Comprehensive Reproductive Solutions for Carrier Couples
If both partners carry the Thalassemia gene, there is a 25% chance that their child will inherit the disease. However, experts advise that couples proactively seek modern medical solutions. One of the most effective methods today is in vitro fertilization (IVF) combined with PGT-M embryo genetic testing, a service currently offered by GENTIS. This approach allows doctors to select healthy embryos free from the Thalassemia gene to be implanted into the mother’s uterus, ensuring the birth of a healthy baby.
In Vietnam, GENTIS leads the way in implementing PGT-M embryo genetic testing. According to Dr. Pham Dinh Minh (R&D Director at GENTIS), with nearly 2,000 IVF cycles and over 3,000 embryos tested for Thalassemia, GENTIS has helped hundreds of families realize their dream of having children without genetic disorders. A major advancement now applied by GENTIS is the One PGT-M solution. This modern technique allows for simultaneous detection of Thalassemia mutations and chromosomal abnormalities (PGT-A/SR) using a single embryo biopsy sample. The method reduces time, optimizes costs, and increases the success rate of treatment.
For families not yet ready for IVF, prenatal diagnostic testing can still be performed to detect genetic abnormalities early and plan appropriate pregnancy care—helping to protect the health of both mother and baby.
Proactive genetic testing and screening should ideally be performed before marriage or early in pregnancy. If a blood test reveals low MCH or MCV levels, even in the absence of family medical history, further genetic testing is strongly recommended. Even when one partner tests negative, it is still essential to test the other partner to ensure a clear genetic profile.
GENTIS – Supporting Families on the Journey to Healthy Children
With a mission to enhance both the physical and mental health of the Vietnamese people, GENTIS continuously innovates and expands its specialized genetic testing services tailored to Vietnamese genetic characteristics. Currently, GENTIS offers two standard Thalassemia screening packages:

The Basic Package, covering 5 common Alpha and 16 common Beta mutations.


The Comprehensive One PGT-M Package, detecting 8 additional Alpha and over 800 Beta mutations—providing a deeper and more thorough gene analysis.



In addition, GENTIS offers advanced genetic counseling services, accompanying clients from initial testing through fertility consultations to embryo selection and transfer. With a team of leading experts and state-of-the-art laboratories, GENTIS has become a trusted destination for thousands of Vietnamese families on their journey to securing a healthy future for the next generation.
Thalassemia can be entirely prevented if detected and addressed in time. With the support of advanced testing technologies and dedicated units like GENTIS, every family can confidently look forward to welcoming a healthy baby—free from genetic disease.
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            [title] => Breakthroughs in the Application of Genetic Testing in Clinical Practice
            [description] => The 10th Can Tho Obstetrics and Gynecology Conference, held on August 22, 2025, welcomed over 1,000 delegates, once again affirming its role as a prestigious scientific forum for the Southern region and the entire obstetrics and gynecology community in Vietnam. With nearly 60 scientific presentations, the conference offered valuable professional insights, ranging from updates in diagnostics and treatment to the growing trend of applying advancements in genetics and precision medicine.
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As part of the conference, GENTIS was honored to accompany two notable presentations by Dr. Nguyen Van Thong, MD (Head of the Department of Medical Genetics, Hung Vuong Hospital), and Dr. Nguyen Huu Trung, MD, PhD (Head of the Department of Obstetrics and Gynecology, University Medical Center HCMC). These presentations demonstrated GENTIS’s pioneering role in the research and development of applied genetic testing in Vietnam.

PGT-UPGRADE Test: Detecting Embryos with Balanced Translocations
Dr. Nguyen Van Thong presented on the topic: “PGT UPGRADE Testing: Detecting Embryos with Balanced Translocations.” His report focused on a challenge frequently encountered by couples undergoing infertility treatment or those with recurrent miscarriages—the presence of balanced translocations in the genome of one partner.
Balanced translocations are genetic abnormalities in which DNA segments are exchanged between non-homologous chromosomes, without any gain or loss of genetic material at the breakpoints. Carriers of balanced translocations often show no symptoms, but are at high risk of producing embryos with chromosomal abnormalities or non-viable embryos. This can result in miscarriage, stillbirth, or the birth of a child with serious genetic conditions. Therefore, detecting and screening embryos carrying balanced translocations is a crucial step in assisted reproductive treatment.
To address this issue, GENTIS has successfully developed the PGT-UPGRADE test, marking a new advancement in preimplantation genetic diagnosis. This technique allows for the identification of embryos carrying the same balanced translocations as the parent, thereby eliminating the risk of passing on reproductive issues to the next generation. As a result, doctors can select healthy embryos with no genetic risks, increasing implantation rates and offering couples a safer pregnancy journey. This is particularly significant for cases with a history of recurrent miscarriage, unexplained fetal loss, or repeated IVF failure.
With high accuracy and an optimized workflow, PGT-UPGRADE not only brings clinical benefits but also helps save time, reduce costs, and ease emotional burdens for patients. This is a major step by GENTIS in transferring advanced technologies into clinical practice, contributing to the sustainable development of reproductive support in Vietnam.
From Expanded Carrier Screening (ECS) to PGT-M: Preventing Rare Genetic Diseases
Alongside this, the presentation by Dr. Nguyen Huu Trung titled “From Expanded Carrier Screening (ECS) to PGT-M – A Strategy to Prevent Rare Genetic Diseases in Vietnam” offered a broader perspective on controlling inherited disorders at their root.
In the context of rising numbers of monogenic diseases and the high cost of treatment, early identification of genetic risks and proactive intervention before pregnancy has become an urgent necessity in modern medicine.

According to Dr. Trung, Expanded Carrier Screening (ECS) can screen for hundreds of genetic disorders in both men and women, helping identify couples who are carriers of the same recessive genetic mutation. If both partners carry the same disease-causing gene, their children have up to a 25% chance of being affected. In such cases, the optimal solution is to use in vitro fertilization (IVF) combined with PGT-M (Preimplantation Genetic Testing for Monogenic disorders) to screen and select embryos free of the disease-causing genes. This represents a shift from “risk detection” to “proactive prevention”—a strategic direction in preventing rare genetic diseases.
GENTIS is one of the pioneers in deploying and optimizing PGT-M testing panels in Vietnam. With a system that includes more than 100 monogenic diseases—covering both common and rare conditions such as Thalassemia, cystic fibrosis, spinal muscular atrophy (SMA), metabolic disorders, Rett syndrome, and more—GENTIS ensures not only broad test coverage but also high accuracy and rapid turnaround times.
This is made possible through the development of a standardized gene database, a synchronized lab system, and a team of highly trained professionals. In addition, GENTIS places strong emphasis on pre- and post-test genetic counseling, helping patients fully understand their results and make informed decisions based on their family circumstances and reproductive goals.
Genetic Testing – A Practical Tool in Modern Clinical Practice
Both presentations shared an important common message: genetic testing is no longer a distant tool reserved for research or major medical centers, but is increasingly becoming an essential part of modern clinical practice. Thanks to the collaboration between leading experts and applied research units like GENTIS, complex genetic medicine techniques are now more accessible, sustainable, and effective for patients than ever before.

GENTIS's presence at the 10th Can Tho Obstetrics and Gynecology Conference was not merely that of a sponsor, but a clear demonstration of its long-term commitment to improving reproductive healthcare quality in Vietnam. Looking forward, GENTIS aims to continue developing modern genetic solutions, aligned with the mission of “early diagnosis – proactive prevention – healthy babies,” and will continue to work hand-in-hand with the medical community to build a better future for the next generations.

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            [title] => GENTIS Proudly Accompanies the Can Tho Obstetrics and Gynecology Conference 2025
            [description] => From August 21–22, 2025, the Can Tho Obstetrics and Gynecology Conference 2025 will officially take place at the Van Phat Riverside Conference Center in Can Tho City. This prestigious professional event brings together leading experts, doctors, and healthcare professionals from top hospitals and medical centers across Vietnam.
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GENTIS is proud to accompany this year’s conference, carrying the mission of improving public health from the genetic foundation, and introducing advanced genetic testing solutions in the field of assisted reproduction.

A Scientific Forum Connecting Obstetrics and Gynecology Experts
The Can Tho Obstetrics and Gynecology Conference is one of the major events in the Mekong Delta region in 2025, providing an excellent opportunity for physicians, researchers, and medical staff to update their knowledge in obstetrics, gynecology, assisted reproduction, and neonatal care.
The conference will feature numerous high-value scientific presentations, focusing on urgent and relevant topics such as:


Updates on diagnostic and treatment protocols for obstetric and gynecological diseases


Modern assisted reproductive technologies


The application of new technologies in prenatal and neonatal care


Genetic research in reproductive medicine


Importantly, the event serves as a platform for experts to share real-world experience, engage in academic exchange, and strengthen collaboration between central and local hospitals, as well as biomedical research units across the country.
GENTIS – Supporting Professional Development and Leading Innovation in Genetic Medicine
As a sponsor, GENTIS brings to the conference an impressive booth, showcasing advanced genetic testing solutions tailored for assisted reproduction – a field that is gaining increasing importance in modern medicine. Some of the key services introduced by GENTIS include:


PGT NEXT: Detection of aneuploidy/monosomy


PGT UPGRADE: Identification of embryos with balanced translocations


PGT-M for 100+ rare diseases: Screening for over 100 monogenic inherited disorders


PGT-MAX 1: High-resolution genetic analysis technology


Thrombophilia: Screening for blood clotting mutation risks


Karyotype: Comprehensive chromosomal analysis


Advanced male fertility tests: Assessing male reproductive health (e.g., AZF, CFTR, sperm DNA fragmentation)


With internationally accredited laboratories (CAP, ISO 15189:2022, ISO 27001:2022, ISO 9001:2015), GENTIS continually invests in cutting-edge technology, analytical software, and expert personnel to ensure accurate, fast, and reliable test results.

A Meaningful Experience for Delegates
At this year’s conference, GENTIS not only showcases technical solutions but also creates an open, interactive space at its exhibition booth on August 22, 2025, offering a memorable and meaningful experience for all attendees. At the GENTIS booth, visitors will have the opportunity to:


Receive direct consultations from experienced specialists on genetic testing services


Learn about how genetic testing is integrated into assisted reproduction workflows to improve IVF success rates


Participate in fun mini-games and win exciting gifts


This is also a valuable opportunity for GENTIS to connect with doctors and listen to real-world challenges, helping refine services and develop more specialized tests tailored to the needs of different patient groups.
Over the years, GENTIS has collaborated with hundreds of medical facilities and clinics across Vietnam, contributing to the early screening and treatment of genetic diseases, supporting fertility treatments, improving population health, and bringing hope to thousands of families.
Reaffirming the Bridge Between Genetic Technology and Clinical Medicine
The Can Tho Obstetrics and Gynecology Conference 2025 is not just a platform for GENTIS to showcase its solutions—it is also a chance to reaffirm its role as a bridge between advanced genetic technology and clinical practice, providing doctors with more effective tools for diagnosis and treatment.
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            [title] => GENTIS Participates in Research on Mosaic Embryo Transfer at the VAGO 2025 National Obstetrics and Gynecology Conference
            [description] => On August 16, 2025, the National Obstetrics and Gynecology Conference (VAGO 2025) was solemnly held at the Sheraton Hotel, Vinhomes Imperia Urban Area, Hai Phong City. This prestigious professional event brought together over 1,000 delegates, including professors, PhDs, doctors, scientists, and healthcare professionals working in obstetrics and gynecology from hospitals and medical institutions both in Vietnam and abroad.
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With more than 50 scientific presentations delivered, VAGO 2025 served as an important scientific forum to update new advancements in the diagnosis, treatment, and reproductive healthcare fields. Key topics discussed at this year's conference included obstetrics, gynecology, gynecologic oncology, assisted reproduction, infertility treatment, and advanced techniques in reproductive medicine.

At the conference, GENTIS was honored to collaborate and provide data for the oral presentation by MSc. Dr. Le Thi Phuong Lan (Vinmec Times City International Hospital), titled: “New Perspectives on Selecting Mosaic Embryos for Transfer.” This was one of the key topics at the conference, attracting significant attention from experts in the field of assisted reproduction. The presentation was pioneering, offering updated perspectives on the approach to and handling of mosaic embryos—a subject previously surrounded by much controversy in reproductive medicine.
Mosaic Embryos – From Prejudice to New Opportunities in Embryo Transfer
According to MSc. Dr. Le Thi Phuong Lan, mosaic embryos refer to embryos containing two or more chromosomally distinct cell lines. Traditionally, these embryos were considered "unqualified" for uterine transfer due to the risk of implantation failure, miscarriage, or fetal abnormalities.
The earliest studies on mosaic embryos date back to 1993 (Delhanty – Day 3 embryos) and 1998 (Evisikov – Day 5 embryos). Statistics show the rate of mosaicism in Day 5 embryos ranges from 2–13%, compared to 2.1% in chorionic villus cells and only 0.2% in newborns.
The detection rate of mosaic embryos heavily depends on the diagnostic method used:

FISH: screens 5–8 chromosome pairs


a-CGH, a-SNP, and NGS: can screen all 23 pairs, with NGS (Next Generation Sequencing) being the most commonly used technique today


Mosaicism may lead to serious consequences such as implantation failure, spontaneous miscarriage, or abnormal fetal development. However, recent insights are gradually changing perspectives on the selection and use of mosaic embryos in embryo transfer.

Factors Influencing the Rate of Embryo Mosaicism
According to Dr. Phuong Lan, there are two main groups of factors influencing mosaicism rates:

 Unavoidable factors:


Patient-related conditions, notably severe sperm abnormalities (SOAT).


Interestingly, female age is not associated with mosaicism—this has been confirmed by recent studies (Viotti, 2021; Girardi, 2020; ASRM, 2023).




 Avoidable and improvable factors:


Ovarian stimulation protocols.


IVF lab techniques: conventional IVF tends to result in higher mosaicism rates than ICSI.


Biopsy techniques (flick vs. laser), culture conditions, and embryologist expertise also play crucial roles.



According to current standards, acceptable mosaicism rates should be below 13% (Elkinmuzo, 2024).
In addition, the quality of the genetic lab is a critical factor. Diagnostic methods, technologies, and genetic data analysis software must meet high accuracy standards to deliver reliable results.
Real-World Study Opens New Pathways
Dr. Phuong Lan’s oral presentation highlighted a large-scale practical study conducted in collaboration between Vinmec International Hospital, GENTIS, and IRMET (Italy), led by Assoc. Prof. Francesca Spinella and colleagues. Conducted on 3,094 cases, this is one of the largest known studies on embryo mosaicism to date.
Key findings of the study include:

Mosaic embryos can be transferred safely if the mosaicism rate is under 50%.


The type of mosaicism (segmental, one chromosome, two chromosomes, or complex) also affects the decision to transfer.


New selection criteria help utilize mosaic embryos that were previously discarded.



Dr. Lan shared: “Previously, mosaic embryos were thought to be abnormal and thus were not transferred. However, in reality, mosaic embryos have the potential to self-correct and can be transferred if they meet specific selection criteria.
Particularly, two key conditions must be met:

A high-quality IVF lab with standard equipment, skilled personnel, and techniques that keep actual mosaicism rates below 13%.


A genetic diagnostic center using modern technology like NGS, accurate data interpretation software, and the ability to make clinically sound decisions.”


This marks a significant advance in reproductive clinical practice, opening new opportunities for couples who do not have euploid embryos available for transfer.

GENTIS – A Pioneer in Genetic Analysis for Assisted Reproduction
As a trailblazer in the field of genetic testing, GENTIS constantly innovates and invests in advanced technologies to best serve the reproductive support needs in Vietnam.
GENTIS is one of the first institutions to implement PGT (Preimplantation Genetic Testing) in Vietnam and has achieved several prestigious international accreditations, including:

CAP (College of American Pathologists)


ISO 15189:2022 – Quality management for medical laboratories


ISO 27001:2022 – Information security management


ISO 9001:2015 – General quality management



With a team of experienced experts, internationally accredited laboratories, and cutting-edge technology, GENTIS continues to play a vital role in improving infertility treatment outcomes, helping thousands of families welcome healthy babies.
Reaffirming the Role in Research and Clinical Application
GENTIS's involvement in this scientific research not only demonstrates its technological and professional capabilities but also reflects its commitment to accompanying the medical community in finding breakthrough solutions to improve infertility treatment in Vietnam.
The genetic data and analysis provided by GENTIS significantly supported Dr. Phuong Lan's study and reaffirmed GENTIS's central role in bridging research and real-world clinical application.
Once again, GENTIS would like to congratulate the outstanding success of VAGO 2025 and sincerely thank the organizers for creating such a meaningful professional forum, contributing to the advancement of obstetrics and gynecology in Vietnam.
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            [title] => GENTIS – A Genetic Bridge Reuniting Distant Hearts
            [description] => In August 2025, a special reunion marked an emotional new chapter for Vietnamese-born Sarah Lou (now living in France) and her biological mother in Phu Tho, Vietnam, after more than 22 years apart. In this deeply moving journey, GENTIS was honored to accompany them and serve as the scientific bridge that confirmed their biological connection—bringing two long-separated hearts back together.
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Sarah Lou, born Bùi Thị Hòa in 2003 in Phu Tho province, was placed in an orphanage shortly after birth due to her family's difficult financial situation. She was later adopted and moved to France. Despite growing up in a completely different environment—language, culture, and country—Sarah always carried within her a profound longing to discover her roots and find her biological parents.
Fueled by that desire, Sarah began her journey to reconnect with her origins with the help of Dan Tri newspaper. Thanks to the efforts of their reporters, the family of Mrs. Hoang Thi Cai and Mr. Bui Minh Son in Phu Tho was identified, with details matching Sarah's story. From that point, GENTIS became the trusted partner in Sarah’s journey, providing precise and reliable DNA testing to verify their familial relationship.
GENTIS – A Bridge of Truth and Family Bonds

As a pioneer in genetic analysis with a reputation for precision and expertise, GENTIS was chosen to carry out the DNA testing between Sarah and Mrs. Hoang Thi Cai.
On August 6, after a rigorous testing process adhering to strict international standards, the DNA analysis confirmed that Sarah Lou is indeed the biological daughter of Mrs. Cải.
Upon receiving the results, Sarah shared:
 “It feels like I’m living in a dream. The happiness is unbelievable. Thank you, Dân Trí, and thank you, GENTIS, for helping me find my real family.”
Sarah’s birth mother, Mrs. Cải, could not hold back her emotions. After more than two decades of pain and regret for placing her daughter in an orphanage, she tearfully said:
 “I never dared to dream that I’d see my daughter again. Thanks to GENTIS, there is no more doubt—my child has truly come home.”
GENTIS – Reconnecting Lives Across Distances

Sarah Lou’s story is not unique. Over the years, GENTIS has conducted numerous DNA tests to help long-lost family members find each other. With state-of-the-art facilities, strict quality control processes, and a team of experienced specialists, GENTIS ensures a high degree of accuracy in every result, allowing every decision to be based on science.
At GENTIS, every DNA test result is more than just a number—it represents hope, truth, trust, and the happiness of an entire family. GENTIS is not merely a testing center—we are a bridge that connects hearts in search of one another.
GENTIS is proud and honored to have been part of Sarah Lou’s journey of reunion. This is not only a triumph of genetic science but also a testament to the deep humanitarian values that GENTIS upholds: Science in service of humanity, of family, and of reconnection.
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            [title] => Total Quality Management – A Perspective from an Expert
            [description] => In a healthcare landscape that increasingly demands precision, safety, and transparency in laboratory testing, the concept of Total Quality Management (TQM) has become a critical factor for modern laboratories. Especially with the rapid development of biotechnology and personalized medicine, laboratories are expected not only to perform accurately but also to meet international standards in performance, equipment, processes, and data security.
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To further clarify this concept, we had a discussion with Dr. Nguyễn Quang Vinh, Director of GENTIS Testing Center, an expert with over 15 years of pioneering experience in building, operating, and optimizing laboratory systems in Vietnam.
- Dr. Vinh, could you share your perspective on the concept of Total Quality Management in laboratories?
Dr. Nguyen Quang Vinh: Total Quality Management (TQM) in laboratories is not simply about controlling the quality of test results. It is a holistic management system that encompasses people, processes, technologies, equipment, and especially aspects related to safety, data security, and continuous improvement.
This system is not solely technical but is built on a customer-centric philosophy, with the ultimate goal of ensuring test results that are accurate, timely, and reliable, effectively serving both patients and treating physicians.
Dr. Nguyen Quang Vinh (Director of GENTIS Testing Center)
The entire system involves participation from all staff—technicians, doctors, administrative personnel, and the management team. Every individual plays a role in maintaining quality and improving performance.
Such a system requires the integration of multiple international quality management standards—not just a single tool or framework. This creates a complex but necessary network to ensure accuracy, biosafety, reliability, and transparent traceability in every operation.
- In your opinion, what standards are essential for building a comprehensive quality management system in laboratories?
Dr. Nguyen Quang Vinh: Comprehensive quality management in laboratories is complex. It requires modern management tools and the integration of multiple standards to create a strong and sustainable system.
First is ISO 9001:2015, a general quality management framework that helps organize operations, control processes, and support continuous improvement.
For labs with advanced equipment, ISO 13485:2016 (for medical device quality management) is essential. It ensures that equipment is not only modern but also safe and effective in operation.
Next is ISO 15189:2022, an international standard that has been recommended and widely adopted by Vietnam’s Ministry of Health. It focuses on technical competence and quality in medical laboratories.
Equally important is ISO 27001:2022, which governs information security and data management—especially relevant as AI and digital technologies become deeply embedded in lab operations.
And finally, we must mention CAP (College of American Pathologists), a highly respected standard from the U.S. for laboratories worldwide. CAP has stringent requirements for performance, quality assurance, internal and external audits.
In my view, these standards must be skillfully, flexibly, and coherently integrated. Meeting each one in isolation without a unified system cannot be considered “comprehensive.”
- To meet international standards, what should Vietnamese laboratories do, Dr. Vinh?
Dr. Nguyen Quang Vinh: First and foremost, adopt a systematic mindset. Quality management should not be seen as a checklist of tasks, but as a continuous, integrated operational flow.
Next is serious investment in equipment, infrastructure, personnel, technology, and processes. Laboratories must be bold enough to adopt challenging standards such as CAP and ISO 15189:2022, which will elevate their capabilities.
And most importantly, it takes patience and long-term commitment. It took GENTIS many years to build our current system, which integrates CAP, ISO 15189:2022, ISO 27001:2022, ISO 13485:2016, and ISO 9001:2015. But in return, we’ve earned trust—from experts, partners both domestic and international, and most importantly, from our patients.
- What are the biggest challenges in building a total quality management system in Vietnam?
Dr. Nguyen Quang Vinh: The biggest challenge is the long-term investment mindset. Quality management is not a cost—it is a value. However, many organizations hesitate because they see adopting multiple standards as expensive or only suitable for large laboratories. Some build a system but fail to maintain it.
Another challenge is the availability of specialized human resources. Implementing international standards requires well-trained personnel with the capacity to operate and continuously improve the system—not just “meet the minimum” and stop there.
Lastly, technology and data. As medical information becomes increasingly digital, managing data, synchronizing processes, ensuring information security, and integrating systems is mandatory, not optional.
- With 15 years of experience in the field, what advice would you give to organizations aiming to upgrade their lab quality management systems?
Dr. Nguyen Quang Vinh: My advice is to build a multi-tiered quality management system, where international standards are not treated as final goals, but as tools to be flexibly integrated into practical operations. This not only enhances credibility but also lays a solid foundation for sustainable international integration.
To achieve this, I believe in focusing on several core principles:

Strong leadership commitment – This is the most critical foundation for achieving consensus and maintaining motivation across the entire system.


Synchronized integration of international standards, including CAP (stringent U.S. standards for laboratories), ISO 15189 (medical lab competency), ISO 13485 (medical device management), ISO 27001 (information security), and ISO 9001 (quality improvement and customer satisfaction).


Continuous staff training – Not just for technical updates, but to develop a mindset of improvement and a deep awareness of quality in every role.


Standardized operational processes – Processes must be clear, executable, auditable, and capable of flexible improvement.


Regular internal assessments – An effective tool to detect errors early, make timely corrections, and sustain system efficiency.


A culture of quality – Most importantly, making “quality” a habit and a core value across all activities, from technicians and doctors to administrative and support teams.


An effective quality management system cannot be built overnight. But with the right direction and long-term commitment, it can not only enhance operational efficiency, but also help build trust among customers and professional partners at home and abroad.
- Thank you, Dr. Nguyen Quang Vinh, for your practical and insightful sharing!
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            [slug] => A-reunion-after-28-years-between-a-french-vietnamese-woman-and-her-biological-parents-in-thanh-hoa-a-connection-of-blood-and-heart
            [title] => A Reunion After 28 Years Between a French-Vietnamese Woman and Her Biological Parents in Thanh Hoa – A Connection of Blood and Heart
            [description] => Among countless stories of human life, sometimes we come across a truly special journey — where family bonds that seemed to fade still quietly live on in every heartbeat. The story of Malia Bakeon (birth name: Bùi Thị Dung), a woman of Vietnamese origin currently living in France, is a deeply moving testament to that truth.
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Born in Thanh Hoa, Malia did not grow up in the embrace of her biological parents due to difficult circumstances. Life led her to France at a very young age, where she was adopted. Though she had a peaceful childhood in a faraway land, Malia Bakeon always carried a deep yearning in her heart — to know who she really was, where she came from, and who brought her into this world.
A 28-Year Journey to Reconnect With Her Roots

For nearly three decades, Malia never stopped thinking about her biological parents. Faint childhood memories gave her the determination to embark on the journey to find her birth family. That journey was far from easy. But thanks to the support of the Vietnamese community, the spread of information through the media, and especially the advances in DNA testing at GENTIS, Malia gradually moved closer to the truth of her origins.
Then, on a special day, a miracle happened: she found her biological parents in Vietnam — after 28 long years of separation. A reunion that had once only existed in the dreams of a little girl finally became reality.
GENTIS – A Bridge of Truth and Love

In that emotional journey, GENTIS is proud to have accompanied Malia as a crucial bridge, confirming the blood ties between her and her family in Vietnam.
Through highly accurate DNA testing, GENTIS helped verify the biological relationship between Malia and her birth parents — a key step in making the long-awaited reunion come true.
At GENTIS, each DNA sample is not just biological data. It is a living story of human connection, of family, and the deep longing to rediscover one’s true self. We understand that behind every result are tears of joy, the laughter of reunion, and the first hugs after many years apart.
GENTIS always places accuracy and professional ethics as its highest priorities. Every DNA test at GENTIS follows strict protocols in line with international standards, supported by modern laboratory systems, a team of experienced experts, and meticulous quality control at every stage.
We don't just deliver results — we restore trust and peace of mind for every client on their journey to uncover the truth.
More Than Just Testing – A Journey to Reclaim One’s Identity

Malia Bakeon's story is not just a personal tale. It is a symbol of hope for thousands longing to reconnect with their roots and biological families.
GENTIS understands that knowing where you belong is a basic yet sacred human need. That’s why in every journey — whether it’s reuniting with birth parents, confirming family relationships, or affirming identity — GENTIS is committed to walking alongside you with the utmost dedication and professionalism.
GENTIS congratulates Malia Bakeon and her family on this miraculous reunion! May the bonds of family continue to grow stronger, bringing days filled with love and connection. We also sincerely thank Malia for choosing and trusting GENTIS. Her story is a source of inspiration that drives us to keep striving, continuing to be a trusted companion for millions of families — on the journey to rediscover their roots and affirm the value of genetic heritage.
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            [slug] => GENTIS-&-Dong-Do-hospital-bringing-genratest-solutions-closer-to-patients-with-infertility-issues
            [title] => GENTIS & Dong Do Hospital – Bringing Genratest Solutions Closer to Patients with Infertility Issues
            [description] => On the afternoon of July 17, 2025, at Dong Do General Hospital, representatives from GENTIS (Genetic Analysis Services JSC) had a working session and professional exchange with the hospital's team of obstetricians and reproductive specialists. The meeting focused on introducing and providing in-depth updates on the Genratest – an advanced tool that improves treatment outcomes in assisted reproductive technology (ART), especially for patients who have experienced repeated implantation failure (RIF).
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The scientific meeting was attended by Dr. Tang Duc Cuong, Level II Specialist – Medical Director of Dong Do Hospital and Director of the Dong Do IVF Center; MSc. Dr. Ngo Thi Diem – Head of the Obstetrics Department of Dong Do Hospital; along with various experts, doctors, technicians, and nurses from the hospital.



During the technical session, MSc. Nguyen Thi Thanh Hang (GENTIS Specialist) presented a scientific report titled "Genratest Technology: Determining the Optimal Window of Implantation (WOI) for Embryo Transfer." The presentation garnered significant attention from all attendees, including medical professionals, technicians, and nurses.
Genratest is a test that analyzes gene expression in the endometrium to precisely determine each woman’s unique Window of Implantation (WOI) – the optimal time when the endometrium is most receptive to embryo implantation. The test involves an endometrial biopsy and next-generation sequencing (NGS) of over 200 genes related to endometrial receptivity. Based on this analysis, doctors can determine the best timing for embryo transfer to achieve the highest success rate.
MSc. Nguyen Thi Thanh Hang provided valuable insights into the Genratest, currently being developed and implemented by GENTIS.
Research shows that among patients with a history of repeated implantation failure, 30–35% have a displaced WOI compared to the standard. This means that continuing with standard embryo transfer timing could result in a high risk of failure – even if the embryo quality and uterine environment are good. Genratest represents a breakthrough in personalized IVF treatment, supporting clinicians in making accurate and timely decisions regarding embryo transfer, thereby increasing implantation rates and reducing unexplained IVF failures.
When questions arose regarding Genratest from Dong Do Hospital’s specialists, Ms. Duong Thi Phuong (Head of R&D at GENTIS) gave detailed explanations on the sampling, analysis, and result delivery process. The endometrial biopsy is taken during a natural or hormone-controlled cycle and processed in GENTIS's ISO 15189-certified laboratory. Results are available within 10–12 working days, giving doctors a scientific basis to adjust embryo transfer timing for the following cycle.
In addition to theoretical aspects, the session also featured notable clinical data from both Vietnamese and international studies. Personalized embryo transfer based on Genratest results has shown significantly improved clinical pregnancy rates. Genratest is considered a valuable tool for patients facing challenges on their journey to parenthood.
Dr. Tang Duc Cuong shared:“We highly appreciate the applicability of Genratest in modern IVF treatments. With a team of skilled doctors and the support of cutting-edge technology, we believe personalized treatment – especially embryo transfer – is the key to improving success rates and reducing the burden on patients.”
Dr. Tang Duc Cuong – Medical Director of Dong Do Hospital and Director of Dong Do IVF Center – engaged in a meaningful discussion about the Genratest solution from GENTIS.
The meeting also set the stage for future collaboration between GENTIS and Dong Do Hospital, particularly in incorporating Genratest into routine treatment protocols and clinical research. This marks a significant step toward enhancing the quality of infertility treatment in Vietnam, making molecular biotechnology more accessible and effective for the community.
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