GENTIS's History of PGT Testing Development

PGT - The Golden Key to Finding Children for Families

The invention of in vitro fertilization (IVF) has helped millions of infertile couples realize their dream of having children after years of waiting. However, couples needing IVF are often older or have issues that reduce the quality of their eggs/sperm. Therefore, embryo transfer often fails or, if successful, may carry risks of having children with birth defects.

Preimplantation genetic testing (PGT) has become an important solution to help couples undergoing IVF achieve successful embryo transfer and give birth to healthy babies.

PGT has become the "golden key" in families' journey to find children, helping to:

• Increase pregnancy rates per embryo transfer
• Reduce miscarriage rates
• Reduce the risk of multiple pregnancies
•  Increase the chance of having healthy children
• Reduce the time and resources needed

Given the immense significance of PGT testing, couples should consider getting tested if recommended by their doctor to increase their chances of successful pregnancy and giving birth to a healthy baby.

History of PGT Testing Development at GENTIS

GENTIS Testing Center is proud to be a pioneer in PGT testing in Vietnam, helping countless families turn their dream of having children into reality. Let's take a look at GENTIS's impressive milestones in its 10 years of PGT testing development.

2013: The first NGS Illumina system for PGS (now PGT) testing was imported to GENTIS.

2014: PGT testing was assessed for its value in use at some of the first IVF centers in Vietnam.

2015:PGT testing was officially implemented in Vietnam.

2016-2018: PGT testing volume increased significantly, with more and more IVF centers referring patients for PGT testing.

2019-2022: PGT became a familiar test for IVF centers nationwide.

2023: GENTIS became the first organization in Vietnam to achieve ISO 15189:2012 certification for PGT-A testing services, a testament to the tireless efforts of all GENTIS Testing Center staff.

Up to now, GENTIS has performed testing for approximately 30 IVF centers in Vietnam, with a volume of over 30,000 embryos per year.

In particular, GENTIS has published numerous scientific research papers on PGT in reputable international journals and presented reports at international conferences, including:

• The research paper "Development and clinical application of a preimplantation genetic testing for monogenic disease (PGT-M) for beta thalassemia in Vietnam" was published in the Journal of Assisted Reproduction and Genetics by the American Society for Reproductive Medicine (ASRM).
• A report on the topic "PGT-M for rare diseases in Vietnam" at the ASPIRE 2021 conference.
• A report on "One case of preimplantation genetic testing for Marfan’s syndrome in Vietnam" at the 19th International Preimplantation Genetic Diagnosis Society (PGDIS) conference.
• A report on "A comprehensive pre-implantation genetic test for alpha and beta thalassemia disease" at the 19th International Preimplantation Genetic Diagnosis Society (PGDIS) conference.

With a 10-year journey of implementing and developing PGT testing, GENTIS has made a significant contribution to helping couples select genetically high-quality embryos, increasing the chances of successful pregnancy when undergoing IVF, ensuring that children born are healthy and free from the screened genetic syndromes.