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GENTIS constantly approaches, researches, and develops new tests, especially clinical applications in ART, to provide accurate, fast, and effective results to help clinicians best treat patients.
Prof. Dr. Nguyen Dinh Tao - Chairman of Hanoi Association of ART
At the 2nd Scientific Conference and Congress for the 2024-2029 term held on March 24, leading experts updated the latest scientific information in the field of ART. A highlight was the presentation by MSc. Nguyen Quang Vinh (Director of GENTIS Laboratory Center) on the topic "Application of PGT-Max 1 test in screening embryos carrying common microdeletions."
According to MSc. Vinh, PGT-Max 1 is a breakthrough improvement over conventional preimplantation genetic testing (PGT). The advantage of this test is that, in addition to being able to detect aneuploidy of 24 chromosomes, chromosomal structural abnormalities (microdeletions, duplications) with a size of more than 5Mb, and mosaic embryos (20% - 80%), it can also detect additional chromosomal structural abnormalities with a smaller size of more than 2Mb related to some common genetic diseases/syndromes such as:
- 22q11.2 deletion (associated with DiGeorge syndrome)
- 1p36 deletion (associated with 1p36 deletion syndrome)
- Some other common microdeletions/microduplications
MSc. Nguyen Quang Vinh (Director of GENTIS Laboratory Center) presents on the topic "Application of PGT-Max1 test in screening embryos carrying common microdeletions."
GENTIS has successfully optimized and applied the PGT-Max 1 test on embryos for many infertile couples wishing to have children. Thanks to the PGT-MAX 1 test, doctors and experts can select embryos with good genetic quality, increasing the chances of pregnancy when performing in vitro fertilization (IVF), helping children to be born healthy and free from screened genetic abnormalities.
At GENTIS, the PGT-MAX 1 test is performed on the most advanced technologies such as NGS sequencers from Illumina USA, specialized bioinformatics software with the highest sensitivity and specificity of up to 99.9%,... "In the future, GENTIS will constantly improve and update new services in the field of assisted reproduction, helping to meet the needs of doctors and help many couples with genetic diseases to give birth to healthy children," MSc. Vinh shared.
According to experts, genetic testing is indispensable in assisted reproduction. However, not all clinicians have in-depth expertise in genetics. Therefore, it is difficult to advise patients to understand the method and limitations of genetic testing, explain cases of unsuccessful implementation, or advise on results after implementation, etc.
Therefore, the combination of clinicians, testing labs, and geneticists is essential to provide the best advice to patients. These issues were clearly shared by Nguyen Thi Huyen, MSc. MD. in the presentation "Genetic counseling in the era of Genomics and personalized treatment."
In the field of ART, genetic counseling plays an extremely important role. Accordingly, geneticists will calculate genetic risks, explain the inheritance pattern of the disease, advise on the principles, advantages, and limitations of testing methods, interpret test results, etc. Thereby, raising awareness and understanding of patients about their genetic risks and making decisions that are beneficial to themselves and their families.
Nguyen Thi Huyen, MSc. MD. presents the report "Genetic counseling in the era of Genomics and personalized treatment"
Most importantly, it supports and advises clinicians, helping them to make the best testing and treatment decisions for patients. "With the mission of 'Improving the physical and intellectual well-being of Vietnamese people,' GENTIS always focuses on researching and developing genetic tests serving precision medicine... Thereby bringing modern solutions, accompanying and supporting doctors in taking care of the health of the community," MSc. Huyen shared.
Besides, the topic "Ovarian rejuvenation with platelet-rich plasma" by Dr. Dang Vinh Dung (108 Military Central Hospital) is also one of the issues of interest to many experts. According to Dr. Dung, the clinical application of platelet-rich plasma (PRP) has increased markedly in the past decade. PRP therapy is widely used in various fields of medicine, including assisted reproduction. PRP is produced from autologous blood samples with the advantages of being easy to perform, limiting the risk of infectious diseases, and immune reactions.
Dr. Dang Vinh Dung (108 Military Central Hospital) presents the report "Ovarian rejuvenation with platelet-rich plasma"
PRP therapy is a promising treatment option for women who want to restore or improve ovarian function and rejuvenation. The application of platelet-rich plasma to rejuvenate the ovaries has been applied in the world for about 2-3 years, especially in the last year, there have been many documents talking about this issue and showing very clear results. Dr. Dung also highly appreciated the effectiveness of the PRP IVF kit used to separate platelet-rich plasma that GENTIS is providing.
Through the reports at the 2nd Scientific Conference and Congress for the 2024-2029 term, GENTIS hopes to have contributed to providing useful knowledge for doctors and experts in the field of assisted reproduction as well as families wishing to have children. With over 13 years of experience, GENTIS will always develop, innovate, and update the best testing services to customers and partners for the mission of improving the physical and intellectual well-being of Vietnamese people.
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