A study by the Italian National Institutes of Health indicates that infertility affects 15% of couples and equally affects men and women.
About 10-15% of male infertility cases and 8-10% of female infertility cases are related to genetic changes, which can include chromosomal abnormalities or single gene mutations.
20% of cases are defined as “idiopathic infertility” because the underlying cause cannot be definitively diagnosed.
FERTISCAN As a test to determine the genetic cause of infertility and the rarest genetic abnormalities associated with infertility and recurrent miscarriages in women; as well as an assessment of male reproductive health, to identify the most common genetic causes of male infertility. It is the first genetic test in Vietnam that analyzes 120 genes simultaneously to help assess the cause of genetic infertility in both men and women. |
70 genes for female infertility linked to
50 genes for male infertility linked to
Is the first genetic test in Vietnam to help evaluate at the same time panel >120 genes that are the genetic cause of infertility in men and women.
FERTISCAN test - WOMEN Simultaneous analysis of 70 genes to determine the cause of female infertility | |
STATUS GROUP | GENE |
Repeated miscarriage | ANXA5,CGB3,KHDC3L,NLRP7 |
Ovarian failure | BMP15,DIAPH2,EIF2B4,EIF2B5,ESR1,ESR2,FANCF,FIGLA,FMR1,FOXL2,GALT,HARS2,HFM1,LARS2,MCM8,MCM9,MSH5,NOBOX,PMM2,POF1B |
Embryos stop developing | TLE6,TUBB8,KHDC3L,PADI6 |
Polycystic Ovary | CAPN10,CYP11A1,CYP19A1,CYP17A1,GDF9 |
Fertilization process | CD46,CDE250,CLPP |
Hypogonadism | FSHB,FSHR,GNRH1,GNRHR,KISS1,KISS1R,PROKR1 |
Others | CYP21A2,EYF2B2,FOXP3,HSD17B4,IRH1,LHB,LHCGR MRPS22,NLRP10,NUP107,OSBPL5,PADI6,PATL2 |
FERTISCAN TEST - MEN Simultaneous analysis of 50 genes to determine the cause of male infertility | |
Status group | GENE |
Sperm morphology | AK7,QURKC,BRDT,CATSPER1,CATSPER2,CFAP43,CFAP69,DP19L2,SUN5,DNAH1 |
Infertility, oligospermia, failed spermatogenesis | ADGRG2,CFTR,NANOF1,TEX11,TEX14,TEX15,CFAP44, DNAH6,FANCM,FHSB,GALNTL5,GATA4,HSF2,SPATA16 |
Disorders of sexual development | AR,LHCRG,NROB1,NR5A1,SRY,FSHR |
Technology: Next Generation Sequencing (NGS) - Full Exome Sequencing Technique.
Samples used: 2 - 3ml of whole blood in EDTA . anticoagulation tubes
Sample preservation: Store in a refrigerator (0-4°C), send samples to GENTIS up to 2 days from the time of sampling
Time to return results: 3-4 weeks (excluding Saturdays, Sundays and public holidays)
Sample collection kit: The kit is housed in a dedicated box provided by GENTIS:
- EDTA blood tube
- Blood collection needle set
- Biosafety bag
- Patient information declaration form
FERTISCAN test at GENTIS
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