Obstetric genetics


GENRATEST - Detect the window of implantation

  • Genratest is a genotypic expression-based analytical test used to determine the optimal time for embryo transfer (window of implantation).
  • Using NGS to analyze the expression of whole genomes related to uterine receptivity status.
  • Based on genotype expression, endometrial lining is divided into 3 types: Pre-reception, Reception and Post-Reception.


  • People who have failed embryo transfer many times (≥ 2 times), good embryo quality and good uterine lining but failed embryo transfer for unknown reasons.
  • ≥1 failed use of recipient eggs, good embryos, good uterine lining, but failed embryo transfer of unknown cause.


1, Study by Katzorke, Vilella, Ruiz, Krüssel, & Simón, 2016, performed on 6,000 patients with embryo transfer failure, up to 28.6% of patients were in a non-recipient state. In which 85% of patients are in the pre-reception state, 12.6% of the patients are in the post-reception state.

2, Study by Tan et al., 2018, on 88 patients with embryo transfer failure in the Genratest group compared with the control group without Genratest, the results were:

  • Increase the rate of successful embryo transfer: 73.7% in the Genratest group compared to 54.2% in the control group.
  • Increase the rate of successful pregnancy: 63.2% in the group using Genratest compared to the control group 41.7%


  • Biopsy of the uterus (P+5 or LH+7), fill out the test request form
  • Put the sample into the storage tube, shake well, store at 4-8oC
  • Transport to GENTIS laboratory with gel ice
  • Sequencing on NGS
  • Analyze results
  • Send the results to the IVF Center (From 12 days after receiving the sample)
  • Transfer embryos according to the recommended date on the results


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