News

News

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            [slug] => ASEM-Test-A-valuable-tool-in-assisted-reproduction
            [title] => ASEM Test - A Valuable Tool in Assisted Reproduction
            [description] => In vitro fertilization (IVF) is currently recognized as one of the most effective and widely used treatments for infertility. To support this technique, numerous new technologies have been developed and applied in clinical practice. Among these, the Analysis of Spent Embryo Medium (ASEM) test, which analyzes the DNA present in the embryo culture medium, has garnered significant attention. This method has been shown to significantly improve pregnancy rates, increase the success of IVF, and reduce the risk of miscarriage.

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Overview of the ASEM Test

Chromosomal aneuploidy is a relatively common condition in human embryos, with rates ranging from 20% to 80% depending on maternal age. Approximately 10% of clinical pregnancies are found to have triploidy or monosomy, and this rate can rise to 50% in older pregnant women. Aneuploidy can lead to implantation failure or be a major cause of recurrent miscarriage.

The ASEM test evaluates the chromosomal genetic status of embryos through the embryo culture medium. 

Preimplantation Genetic Testing for Aneuploidy (PGT-A) is currently recommended for couples undergoing IVF to select embryos without chromosomal aneuploidy for transfer. 

PGT-A has been shown to increase successful embryo transfer rates, shorten the time to conception through euploid embryo transfer, and reduce the number of transfers, miscarriage rates, and overall costs, especially in older women. To perform PGT-A, embryo biopsy is required to obtain the necessary material for testing.

In contrast, the ASEM test (Analysis of Spent Embryo Medium) assesses the chromosomal genetic status of embryos through the embryo culture medium without requiring an embryo biopsy. The ASEM test is based on the presence of cell-free DNA (cfDNA) in the culture medium. Studies have shown that blastocyst culture medium can be used to evaluate the genetic status of embryos.

Advantages of the ASEM Test

Because the ASEM test is performed on the embryo culture medium, it is non-invasive and safe. 

Unlike traditional methods that require embryo biopsy, the ASEM test offers several notable advantages:

  • Reduced Costs: It eliminates the need for equipment investment for embryo biopsy and the requirement for skilled embryologists to perform the biopsy.
  • Non-Invasive: The ASEM test does not disturb the embryo, which is particularly beneficial for poorly developing embryos where biopsy could be detrimental. It allows for the assessment of chromosomal aneuploidy before embryo transfer without invasive procedures.
  • Useful in Certain Situations: In cases where embryo biopsy for PGT-A cannot be performed for various reasons, the ASEM test provides valuable genetic information about the embryo.

The Role of the ASEM Test in Assisted Reproduction

The ASEM test represents a breakthrough in genetic diagnosis and is a valuable tool in the field of assisted reproduction. When combined with morphological evaluation, it helps select embryos with the best potential for transfer in cases where embryo biopsy for PGT-A is not feasible. The goal is to increase the success rates of embryo transfers and reduce miscarriage rates for infertile couples.

ASEM Testing at GENTIS

GENTIS is the first institution in Vietnam to implement and offer the ASEM test. Mr. Nguyen Quang Vinh, MSc, Director of the GENTIS Testing Center, stated: "GENTIS continues to research and evaluate the effectiveness of the ASEM test to improve the quality of IVF/ICSI cycles, with the aim of enhancing successful embryo transfer rates."

To assess the clinical effectiveness of the ASEM test, GENTIS has collaborated with several hospitals and assisted reproduction centers nationwide. Notably, GENTIS and Hanh Phuc International Hospital conducted a study titled "Evaluation of the Effectiveness of Genetic Analysis of Embryo Culture Medium." 

The study compared clinical outcomes between two groups: one that selected embryos for transfer based solely on morphological evaluation (control group) and another that used both morphological evaluation and ASEM test results (study group). The study found live birth rates of 38.6% in the control group and 41.1% in the study group. Additionally, the miscarriage rate in the study group was 0% (no miscarriages were recorded) compared to 12.9% in the control group.

These preliminary findings suggest that the ASEM test has the potential to increase live birth rates and significantly reduce miscarriage rates. This is crucial in preventing the physical and emotional trauma associated with miscarriage.

The initial successes of the ASEM test further solidified GENTIS’s leading position in the field of genetic analysis in Vietnam. GENTIS hopes that the ASEM test will become a routine clinical practice in hospitals and IVF centers worldwide, bringing joy and happiness to couples of reproductive age who need medical assistance to conceive and give birth to healthy babies.

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To foster cooperation and advance research on a range of new services, GENTIS organized the seminar at Ngoc Bich General Hospital in Nam Dinh. The event featured the participation of Dr. Nguyen Van Hoa, Chief Medical Officer; Dr. Nguyen Van Hung, Deputy Director of the hospital; Dr. Vu Duy Trong, Deputy Head of Surgery; Mr. Tran Minh Chau, Head of the Planning Department; along with over 20 other doctors and medical staff from the hospital. GENTIS was represented by Ms. Le Thi Hong Nhung from the product management department.

During the seminar, presenter Le Thi Hong Nhung provided a detailed report on various tests currently being researched and developed by GENTIS. These tests have significant implications in the fields of reproductive health, obstetrics, and pediatrics, and include:

- Non-Invasive Prenatal Testing (NIPT) - GenEva

- Newborn Screening

- Thalassemia Testing

- Thrombophilia Testing

- Antiphospholipid Syndrome Testing

- HPV Testing - EPREP

The seminar began with a comprehensive presentation by Ms. Hong Nhung on GENTIS's GenEva NIPT, a non-invasive prenatal screening test. This test can detect chromosomal abnormalities in fetuses, such as Down syndrome, Edwards syndrome, Patau syndrome, and microdeletions/microduplications.

The test is performed through maternal blood sampling, ensuring safety for both the mother and the fetus. The testing process is optimized, fast, and provides results with an accuracy rate of over 99%.

Additionally, the newborn screening tests offered by GENTIS garnered significant interest from the attending medical staff. Newborn screening is regarded as one of the most effective methods for early detection of abnormalities in infants, allowing for timely intervention and preventing severe complications and damage.

Moreover, newborn screening increases survival rates, reduces the impact of diseases, extends patient lifespans, and helps save on healthcare costs.

As part of the seminar, Ms. Hong Nhung also presented on tests for Thalassemia, Thrombophilia, Antiphospholipid Syndrome, HPV - EPREP, and more.

During the seminar, the doctors, nurses, and medical staff had their questions and concerns addressed directly and thoroughly by Ms. Hong Nhung. The seminar concluded successfully



Following this service update seminar at Ngoc Bich General Hospital, GENTIS hopes that the medical staff have gained valuable information to better advise their patients, ultimately reducing the birth of children with diseases, easing the burden on families and society, and bringing happiness to families across Vietnam.

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On the occasion of the 75th anniversary of the Vietnam Military Medical Academy (March 10, 1949 - March 10, 2024), the Academy organized a scientific conference themed "Updating Knowledge, Applying Technology, Enhancing the Quality of Protection and Healthcare for Soldiers and People" on March 4-5, 2024.

Taking place over two days, the Continuing Medical Education (CME) program and the official scientific conference attracted over 500 delegates, encompassing training topics such as:

CME1: Updating Breast Reconstruction and Reconstructive Surgery Techniques and Post-Breast Cancer Treatment Complications.

CME2: Infection Control

CME3: Assisted Reproductive Techniques

The plenary session featured numerous reports from international experts, including:

+ The Status and Advances in Organ Transplantation in Vietnam - Prof. Dr. Pham Gia Khanh, Vietnam Organ Transplantation Association

+ Application of Modern Medical Technology in the Treatment of Injured and Victims - Prof. Ivchenko E.V., S.M Kirov Military Medical Academy, Russian Federation

+ Asia-Pacific Initiative for One Health Cooperation to Combat Antimicrobial Resistance (AMR) - Prof. Motoyuki Sugai, National Institute of Infectious Diseases, Japan

Topic 1: Military Medicine

Topic 2: Infection Control and Prevention of Infectious Diseases

Topic 3: Surgery and Plastic Reconstructive Surgery

Topic 4: Internal Medicine and Cancer

Topic 5: New Advances in Biotechnology and Biomedical Sciences

Topic 6: Dioxin and Occupational Diseases

GENTIS Company was honored to be a sponsor of the conference, presenting a direct report and providing research and report materials for the conference; simultaneously sharing insightful and in-depth information on genetic issues in assisted reproduction during the CME3 session.

In his role as chair of the CME3 session, Prof. Dr. Nguyen Dinh Tao (President of the Assisted Reproduction Association) coordinated the program and provided clear insights into the importance of genetic testing in assisted reproduction.

The training session began with a presentation by Assoc. Prof. Dr. Le Hoang (Director of the Assisted Reproductive Technology Center, Tam Anh General Hospital) on the topic "The Role of Genetics in Assisted Reproduction," which attracted the attention of numerous attending doctors. According to Assoc. Prof. Le Hoang, the integration of genetics and assisted reproduction creates new prospects for enhancing treatment effectiveness for infertile patients. Moreover, it is crucial to focus on developing experts in the field of genetics to support clinical doctors. Ordering, counseling, and interpreting genetic test results will be a challenge for clinical doctors who have not yet had much exposure to this field.

The next presented topic, "Mosaic Embryo Transfer: International Recommendations and Clinical Practice in Vietnam," shared by Assoc. Prof. Dr. Ho Sy Hung (Deputy Director of the National Assisted Reproductive Technology Center, Obstetrics and Gynecology Hospital), garnered significant interest from assisted reproduction doctors. In this report, GENTIS was honored to provide survey data from the National Assisted Reproductive Technology Center in 2023, with 513 embryos examined, revealing a mosaic embryo rate of 30.6%. The associate professor also highlighted points to consider when interpreting embryo test results in cases of mosaicism, and the order of priority for transferring mosaic embryos according to international standards and clinical practice in Vietnam.

Beyond female treatment, the topic of male infertility, "Y Chromosome Abnormalities Causing Infertility," was also an engaging presentation by Assoc. Prof. Dr. Trinh The Son (Director of the Military Clinical Embryo Institute). The associate professor identified Y chromosome abnormalities such as translocations, microdeletions, and Y chromosome numerical abnormalities causing various male infertility conditions like 46,XX; AZF a,b,c deletions; Klinefelter; 47,XYY… From there, Assoc. Prof. Son shared clinical experiences of successfully treated male infertility cases and numerous studies conducted worldwide.

At the end of the CME3 training session, Dr. Pham Dinh Minh (Director of GENTIS R&D Center) provided clinical doctors with an update on the topic "Applying Advances in Biotechnology to Develop Gene and Genetic Tests in Assisted Reproduction." As a pioneer in the field of genetics, GENTIS has provided a comprehensive gene ecosystem for applications from the pre-pregnancy, pregnancy, and healthy childbirth stages. Dr. Minh particularly emphasized the role of genetic doctors and genetic counseling for patients to ensure the best treatment options for infertile families.

The program concluded with lively discussions from participating delegates revolving around topics such as: screening and diagnostic testing for Thalassemia and methods to help families with the disease have healthy children; follow-up recommendations for pregnancy after mosaic embryo transfer; the potential of embryo culture environment analysis in assisted reproduction…

The Scientific Conference Celebrating the 75th Anniversary of the Vietnam Military Medical Academy was a resounding success, coordinated and presented by leading experts in the field of assisted reproduction. Once again, GENTIS congratulates the conference and invites you to revisit some photos from the event!

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Coffee talk is a series of programs organized by the Genetic Counseling Center (GENTIS) for clinicians, embryologists, lab technicians, … across the country with specialized themes centered around the field of assisted reproduction. The event is a bridge for people to exchange, share, exchange knowledge, medical experience, genetic counseling with leading experts in the field of assisted reproduction.

Host and Speakers of the Coffee Talk event: Genetic counseling in the field of assisted reproduction No. 1:Specialist Consultation of PGT Testing

Currently, genetic counseling in assisted reproduction is important but still a difficult topic. Therefore, there should be mutual exchange, support, agreement between clinicians, genetic specialists, embryologists and laboratory tests.

Understanding that, the Genetic Counseling Center of GENTIS held a Coffee Talk: Genetic Counseling in the field of assisted reproduction No. 1 entitled "Specialist Consultation of PGT testing”. The event was hosted by Assoc.Prof. Trinh The Son PhD.MD. - Director of the Military Institute of Clinical Embryo Histology and Nguyen Khac Han Hoan, PhD.MD. - Vice President of the Vietnam Association of Medical Genetics - Head of the Department of Medical Genetic Testing, Tu Du Hospital.

In addition, the Coffee Talk No. 1 session was also attended by speakers, including clinicians, embryologists, genetic physicians and laboratory experts: Le Vu Hai Duy, MSc.MD. - High-tech Center for infertility and andrology, Phuong Dong General Hospital; Specialist level 1 Ho Van Thang, MD. - Specialist in Assisted Reproduction - Hanoi Hospital of Andrology and  Fertility; Vu Dinh Dac, MSc.MD. - Head of IVF Lab - Assisted Reproduction Center, An Thinh Hospital of Obstetrics and Gynecology. Hoang Thi Thuan, MSc.MD. - Head of IVF Lab at Hong Ngoc - Phuc Truong Minh Center for Reproductive Medicine and Fertility; Nguyen Quang Vinh, MSc. - Director of GENTIS Testing Center and Nguyen Thi Huyen, MSc.MD. - R&D GENTIS Specialist.

Speaking at the opening of the event, Mr.Do Manh Ha - General Director of GENTIS Company hopes that the Coffee Talk event series will become a reliable forum for experts, doctors, technicians to exchange, share and learn from experience in the field of assisted reproduction.

Throughout the program, speakers talked about the difficulties and challenges of clinicians, embryologists, genetic testing labs, genetic consultants when performing and using PGT tests. Preimplantation genetic testing (PGT) or embryo screening tests with three main types: screening of abnormal chromosomal quantities, screening of abnormal chromosomal structure, and screening for single-gene disease.

Coffee talk event No. 1 attracted the attention of a large number of clinicians, embryologists, and laboratory specialists,...

All three of these techniques are being routinely applied in IVF centers in Vietnam. However, there are still some problems with standardization, how to improve quality, when to consult before implementation, to designate the right group of patients to be performed, to advise on PGT test results, to consider embryo transfer,... Those are the issues discussed at this Coffee talk. Under the chairmanship of Assoc.Prof.Trinh The Son, PhD.MD. and Nguyen Khac Han Hoan, PhD.MD.,, the speakers also shared practical problems, suggestions and solutions to improve the quality of PGT testing.

The sharing session was very open and in-depth on each issue, bringing a lot of useful information, helping experts better understand PGT testing. Closing the event, Assoc. Prof. Trinh The Son, PhD.MD. shared: "I am very happy to participate in Coffee Talk No. 1 as the chairman, I hope GENTIS Genetic Counseling Center will soon launch sessions 2 and 3 with more attractive and useful topics".

Mr.Do Manh Ha - General Director of GENTIS rewarded certificates to hosts and speakers participating in the talkshow

Coffee talk No. 1 was a great success, GENTIS Genetic Counseling Center would like to express its sincere thanks to the chairmans, speakers and guests who attended. The enthusiastic response of attendees is a great motivation for the Genetic Counseling Center to organize many more Coffee Talks to answer all your questions and concerns about the field of assisted reproduction.

Hopefully, the perspectives and stories shared in the last Coffee talk No. 1 have helped the work of experts. Please follow and update regularly about the program on GENTIS' fanpages and websites.

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In the celebration of the 75th Anniversary of the Military Medical Academy's Traditional Day, GENTIS is honored to sponsor and partner with the Academy in a CME-certified continuing education training program. This significant event aims to provide reproductive medicine professionals with the latest advancements in genetics and clinical practice.

  • A completely FREE in-person training course that is equivalent to 04 academic hours
  • Teaching by leading experts in the field of assisted reproduction.
  • Featuring diverse content and experiences about clinical practice, providing valuable insights for physicians.

CME 2 Topic: "Assisted Reproductive Techniques":

  • Mosaic Embryo Transfer: International Guidelines and Clinical Practice in Vietnam - Assoc. Prof. Ho Sy Hung, Ph.D. (Deputy Director of Assisted Reproduction Center, National Hospital of Obstetrics and Gynecology)
  • The Role of Genetics in Assisted Reproduction - Assoc. Prof. Le Hoang, Ph.D. (Director of Assisted Reproduction Center, Tam Anh General Hospital)
  • Y Chromosomal Abnormalities in Male Infertility - Assoc. Prof. Trinh The Son, Ph.D. (Director of Military Institute of Clinical Histology and Embryology, Military Medical Academy)
  • Advanced Applications of Biotechnology in Developing Genetic Tests for Assisted Reproduction - Pham Dinh Minh, Ph.D. (Director of R&D Center, GENTIS)
  • Chairman: Prof. Nguyen Dinh Tao, Ph.D. - President of the Hanoi Assisted Reproduction Association

We cordially invite you to participate in the CME Training Program at the Scientific Conference celebrating the 75th Anniversary of the Military Medical Academy's Traditional Day.

  • Registering link: 

https://ee.kobotoolbox.org/x/Acc7WAsl?fbclid=IwAR3ihOHI8S3LEpxjLzDwpS32n95guc6O-_dn0UZEy9yzdteHKAjhtSStSJU

  • Date and time: 1:30 PM - 4:30 PM, March 4th, 2024
  • Location: Military Medical Academy, 160 Phung Hung Street, Phuc La, Ha Dong, Hanoi
  • Format: In-person training with complimentary CME certification (equivalent to 4 academic hours)

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European Society of Gynecology - ESG  is a prestigious international organization in the field of Obstetrics and Gynecology. Since 1995, ESG conferences have brought together the world's leading experts in the field to exchange knowledge, share clinical research and professional experiences. These conferences typically occur every two years. In 2023, the 15th conference  of ESG took place from November 29th to December 2nd in Amsterdam, Netherlands. 

As a globally recognized organization, the scientific reports presented directly at the conference undergo a rigorous selection process. At the 2023 conference, Vietnam was honored to be the sole representative with a directly presented report from the research team of GENTIS and Hanoi Hospital of Andrology and Infertility on Preimplantation Genetic Testing for Monogenic Disorders (PGT-M).

Specialist level I Ho Van Thang, a Reproductive Medicine Specialist at Hanoi Hospital of Andrology and Infertility, along with his research team from the hospital and GENTIS, successfully submitted their research paper. After passing rigorous international peer review, they were honored to be the sole Vietnamese representative to give a live presentation at the main session on November 30th. Their presentation focused on "Initial evaluation of preimplantation genetic testing for monogenic disorders (PGT-M) in patients with single-gene genetic diseases”.

PGT-M is a genetic test that enables couples carrying genetic diseases to select embryos that are free from the specific genetic mutations causing the disease. This allows them to transfer healthy embryos to the mother's uterus, preventing the transmission of genetic disorders to the next generation. In a collaborative study conducted by GENTIS and Andrology and Infertility Hospital of Hanoi from January 2020 to May 2023 involving over 20 couples (excluding those with Thalassemia), PGT-M was used to screen embryos for various genetic disorders, including autosomal dominant (polycystic kidney disease), autosomal recessive (spinal muscular atrophy; Arthritis - kidney dysfunction - cholestasis; hemophagocytic lymphohistiocytosis; Atypical hemolytic-uremic syndrome; X-linked Duchenne muscular dystrophy; hemophilia A; hemophilia B; X-linked myotubular myopathy). The clinical outcomes demonstrated a pregnancy rate of 66.7% and a live birth rate of 29.2%.

The report highlighted the significant role of preimplantation genetic testing (PGT-M) in helping couples with monogenic disorders have healthy offspring. A close collaboration among clinical physicians, genetic specialists, and embryologists is essential for accurate diagnosis, effective treatment, and optimal outcomes for patients undergoing in vitro fertilization.

Specialist level I Ho Van Thang's presentation at the main plenary session garnered significant interest and discussion from representatives of healthcare organizations worldwide, particularly those with advanced reproductive medicine programs.

Participating in the 15th European Society of Gynecology Conference provided a valuable opportunity for GENTIS and Hanoi Hospital of Andrology and Infertility to connect with the global reproductive medicine community. The presentation showcased the results of years of dedicated research aimed at developing innovative technologies and improving treatment outcomes for infertile couples. This aligns with GENTIS's long-term goal of helping more couples realize their dream of parenthood.

[content_more] => [meta_title] => GENTIS and Hanoi Hospital of Andrology and Infertility collaborated on research [meta_description] => On November 30th, 2023, GENTIS and Hanoi Hospital of Andrology and Infertility proudly presented their research on Preimplantation Genetic Testing for Monogenic Disorders (PGT-M) at the 15th European Society of Gynecology Conference in Amsterdam, Netherla [meta_keyword] => Gentis,pgt-m,Hanoi hospital of andrology and infertility [thumbnail_alt] => [post_id] => 1182 [category_id] => 4 ) [6] => stdClass Object ( [id] => 1179 [id_crawler] => [category_product] => NULL [thumbnail] => dsc01101.jpg [album] => [url_video] => [is_status] => 1 [is_featured] => 0 [is_form] => 0 [displayed_time] => 2024-02-05 [program] => 0 [number] => 1 [viewed] => 0 [type] => [type_career] => [level] => [address] => [address_career] => [expiration_time] => 0000-00-00 [created_time] => 2024-02-05 08:26:41 [updated_time] => 2024-09-04 11:28:56 [files] => [salary] => [time] => [created_by] => 63 [is_table_content] => 1 [language_code] => en [slug] => Early-screening-of-thalassemia-a-need-for-couples-who-are-both-disease-gene-carriers [title] => Early screening of Thalassemia - A need for couples who are both disease gene carriers. [description] => Thalassemia is the most common monogenic genetic disorder today, causing serious consequences for the race, affecting the lives of patients and the whole community. Therefore, thalassemia testing is necessary to detect the disease gene early to help minimize treatment costs and limit the birth of suffered children. [content] =>

The "dream-like" happiness of a couple both carrying disease gene

Mr. Huy (1983) and Ms. Doanh (1995) in Soc Son, Hanoi had spent about 7 years looking for their children. It can be said that the journey to find their children is more difficult than other couples because Mr. Phu’s legs were bilaterally paralyzed after an accident, and all personal activities almost depend entirely on others. When visiting the hospital, the doctor advised the family to perform a number of tests to find the cause, and found that both Mr. Phu and Ms. Doanh carried the thalassemia gene (congenital hemolysis).

Moreover, 2 miscarriages, 3 failed embryo transfers created a lot of pressure for him and his wife and the treating doctors. Sad, disappointed, but the desire for children and the love that had been wrapped up for 7 years motivated him and his wife to continue to accompany the Vietnamese-Belgian Hospital of Andrology and Infertility (Vietnam -  Belgium IVF).

The happy small family of Mr. Huy and Ms. Doanh

Despite the difficulties, they are still very persistent. Perhaps it was that persistence, perseverance and belief in doctors of the Vietnam - Belgium IVF that created a miracle in the 4th embryo transfer. Baby Minh Dat is the sweet fruit for Mr. Phu and Ms. Doanh's diligent journey to find their children.

However, because economic conditions did not allow it, when doing IVF, they did not perform the preimplantation genetic diagnosis technique. In the case of both husband and wife carrying the thalassemia gene and giving birth naturally, there is a 25% chance that the child will be born with the disease, 50% risk of carrying the disease gene and 25% chance that the healthy child will not carry the disease gene.

With the desire to share, help and support part of the funds to help Mr. Huy's family reduce financial pressure, GENTIS sponsored a thalassemia test to screen Minh Dat early. Fortunately, the results showed that the baby only carried the disease gene.

Receiving the Thalassemia test results, Ms. Doanh choked up emotionally and shared, "My family is grateful and feels very lucky than many people because the baby only carries the disease gene. I wish fathers and mothers who are on the way to find their children will soon pick sweet fruits."

So how is Thalassemia diagnosed?

According to Dr. Ngo Thu Ha (Department of Obstetrics and Infertility of Vietnam Belgium IVF), to diagnose Thalassemia, we should first pay attention to the clinical manifestations and appearance of the patient such as a protruding forehead, flat nose, protruding teeth, enlarged liver, jaundice,... Next, we will do a complete blood count test to check the size of red blood cells. This value is reflected in the mean corpuscular volume index (MCV) and the mean corpuscular hemoglobin (MCH) in your complete blood count test (CBC). If your MCV is <= 85fl and your MCH <=28pg, you are at high risk of carrying a gene mutation that causes thalassemia leading to anemia.

Dr. Ngo Thu Ha (Department of Obstetrics and Infertility of Vietnam Belgium IVF) examines and consults patients

To determine if you have thalassemia, it is necessary to do a hemoglobin electrophoresis test and determine the content of ferritin in the serum, a thalassemia gene test. The implementation of this test will help accurately identify patients with the alpha or beta Thalassemia gene, support doctors in diagnosing and treating the disease effectively, as well as appropriate reproductive advice.

In case the parents are both carriers of the Thalassemia gene, the doctor will advise the patient to do IVF and genetic screening before PGT embryo transfer. This technique helps to select embryos that do not carry disease genes to transfer into the mother's uterus to give birth to healthy babies, contributing to improving the quality of the population.

Currently, GENTIS is accompanying many hospitals and IVF centers to carry out genetic screening before embryo transfer to help many families carrying the disease gene give birth to healthy children. Thalassemia testing at GENTIS uses molecular biology, PCR, and gene sequencing methods to simultaneously identify 21 α-thalassemia and β-thalassemia mutations and rare mutations that cause thalassemia in Vietnamese population. At the same time, homozygous or heterozygous mutant genotypes can be detected.

Standardized Thalassemia gene testing at GENTIS.

Notably, the Thalassemia test at GENTIS showed screening results that detected disease genes with 99% accuracy. In particular, GENTIS gathers a team of scientists, experienced consultants in the field of genetics, and a team of professional technicians and consultants. Contact hotline 1800 2010 for the most dedicated advice and testing!

[content_more] => [meta_title] => Early screening of Thalassemia - A need for couples who are both disease gene carriers. [meta_description] => thalassemia testing is necessary to detect the disease gene early to help minimize treatment costs and limit the birth of suffered children [meta_keyword] => Gentis,thalassemia [thumbnail_alt] => [post_id] => 1179 [category_id] => 4 ) [7] => stdClass Object ( [id] => 1176 [id_crawler] => [category_product] => NULL [thumbnail] => z5094252485725_aa8c33aca27df2860e8cd2c7c1cd7621.jpg [album] => [url_video] => [is_status] => 1 [is_featured] => 0 [is_form] => 0 [displayed_time] => 2024-01-27 [program] => 0 [number] => 1 [viewed] => 0 [type] => [type_career] => [level] => [address] => [address_career] => [expiration_time] => 0000-00-00 [created_time] => 2024-01-27 13:15:45 [updated_time] => 2024-09-04 11:16:11 [files] => [salary] => [time] => [created_by] => 63 [is_table_content] => 1 [language_code] => en [slug] => Genetic-counseling-in-assisted-reproductive-technology-with-Prof-Dr-Nguyen-dinh-tao-and-assoc-prof-dr-tran-duc-phan [title] => Genetic Counseling in Assisted Reproductive Technology with Prof. Dr. Nguyen Dinh Tao and Assoc. Prof. Dr. Tran Duc Phan [description] => On January 24, the GENTIS Genetic Counseling Center broadcasted the talk show "Genetic Counseling - Discussion with Experts" on the topic of "Genetic Counseling in Assisted Reproductive Technology (ART) - The Role of Genetic Counselors and Testing Labs" on the GENTIS fanpage. The event attracted significant attention from medical professionals working in the field of assisted reproduction, as well as from clients interested in undergoing IVF. [content] =>

Led by Prof. Dr. Nguyen Dinh Tao (President of the Hanoi of Society Assisted Reproduction), Assoc. Prof. Dr. Tran Duc Phan (President of the Viet Nam Medical Genetics Association), and Dr. Pham Dinh Minh (Director of R&D and Director of the GENTIS Genetic Counseling Center), the talk show covered genetic knowledge and methods to increase the success rate of in vitro fertilization (IVF) in a straightforward and practical manner, through real-life stories.

Speaking on the significance of the talk show, Prof. Dr. Nguyen Dinh Tao remarked, “In the field of assisted reproduction, there are still many areas that require further research. For couples struggling with infertility, having a child is a deeply held wish, and having a healthy child is a genuine hope, not just for the family but for society as well. To ensure the birth of healthy babies, we must continue to research and understand many aspects, particularly the genetics of the embryo, such as whether the embryo has genetic defects or chromosomal abnormalities. This is where the role of genetic counselors becomes crucial.”

Assoc. Prof. Dr. Tran Duc Phan added, “Today, infertility rates are increasing and tend to affect younger people. Current advancements in genetics are significant; following the sequencing of the human genome, these genetic advancements now help us to conceive and ensure that future children can avoid inheriting certain diseases previously present in the family.”

The talk show "Genetic Counseling - Discussion with Experts" featured participation from Prof. Dr. Nguyen Dinh Tao, Assoc. Prof. Dr. Tran Duc Phan, and Dr. Pham Dinh Minh.

It is clear that genetic testing and counseling play a crucial role in assisted reproduction and healthcare in general. Modern genetic tests have made great strides and are now involved in many stages, including tests related to the parents, the embryo, the embryo transfer process, and newborn screening. The advancement of genome sequencing technology has provided various solutions for detecting genetic diseases, helping doctors to develop the best treatment plans for their patients.

Meanwhile, genetic counseling combines clinical expertise with each patient’s test results, providing information on the likelihood of inherited diseases in future generations of families with such conditions. It also offers advice on marriage, reproduction, and strategies to prevent and reduce negative outcomes in the next generation. This is the core responsibility of genetic doctors: diagnosing and providing genetic counseling.

Dr. Pham Dinh Minh commented, “The 2023 American Society for Reproductive Medicine (ASRM) conference also highlighted that genetics is one of the main drivers of the ART field, not only helping to identify the causes of infertility but also assisting doctors in finding the best treatment methods. With over 13 years of experience in genetic analysis, GENTIS is a pioneer in applying the latest equipment and technology in gene sequencing for testing, as well as in assisted reproduction. GENTIS is committed to researching and developing valuable tests to provide clients with high-quality services. GENTIS operates labs that meet international standards such as ISO 13485:2016, ISO 15189:2012, and aims for CAP accreditation from the U.S. to deliver the best possible testing quality. Additionally, GENTIS has established the Genetic Counseling Center to help clinical doctors and IVF centers accurately and effectively interpret results.”

During the program, the experts addressed the concerns and questions of participants regarding their journey to parenthood using assisted reproductive methods. The extensive knowledge shared by Prof. Dr. Tao, Assoc. Prof. Dr. Phan, and Dr. Minh provided invaluable insights.

It is hoped that the experts’ insights will motivate couples facing infertility on their journey to parenthood. Although the path may be challenging and arduous, with determination, success is possible. Trust that when the time is right, your beloved child will arrive.

[content_more] => [meta_title] => Genetic Counseling in Assisted Reproductive Technology with Prof. Dr. Nguyen Dinh Tao and Assoc. Pro [meta_description] => On January 24, the GENTIS Genetic Counseling Center broadcasted the talk show "Genetic Counseling - Discussion with Experts" on the topic of "Genetic Counseling in Assisted Reproductive Technology (ART) [meta_keyword] => Gentis,GeneticCounseling [thumbnail_alt] => [post_id] => 1176 [category_id] => 4 ) )

ASEM Test - A Valuable Tool in Assisted Reproduction

In vitro fertilization (IVF) is currently recognized as one of the most effective and widely used treatments for infertility. To support this technique, numerous new technologies have been developed and applied in clinical practice. Among these, the Analysis of Spent Embryo Medium (ASEM) test, which analyzes the DNA present in the embryo culture medium, has garnered significant attention. This method has been shown to significantly improve pregnancy rates, increase the success of IVF, and reduce the risk of miscarriage.

Seminar on GENTIS Testing Services Updates at Ngoc Bich General Hospital

On the afternoon of March 6, 2024, GENTIS successfully collaborated with Ngoc Bich General Hospital to host a seminar aimed at updating GENTIS testing services for the hospital's medical staff.

GENTIS Partners with the Scientific Conference Celebrating the 75th Anniversary of the Vietnam Military Medical Academy

On the occasion of the 75th anniversary of the Vietnam Military Medical Academy, the Academy organized a scientific conference themed "Updating Knowledge, Applying Technology, Enhancing the Quality of Protection and Healthcare for Soldiers and People" on March 4-5, 2024. GENTIS was honored to be a sponsor of the conference, providing research and report materials; simultaneously sharing insightful and in-depth information on genetic issues in assisted reproduction during the CME3 session.

GENTIS Genetic Counseling Center successfully organized Coffee Talk No. 1: Specialist Consultation of PGT Testing

On March 2nd, the GENTIS Genetic Counseling Center (affiliated with the Genetic Analysis Joint Stock Company) successfully held a Coffee Talk: Genetic Counseling in the field of digital assisted reproduction with the theme: Specialist Consultation of PGT testing. The event attracted the attention of about 60 experts who are clinicians, genetic physicians, embryologists and lab specialists.

GENTIS sponsors the CME2 Training Course at the Scientific Conference Celebrating the 75th Anniversary of the Military Medical Academy's Traditional Day

On March 4, 2024, GENTIS proudly collaborated with the Military Medical Academy in a CME-certified continuing education training program focusing on "Assisted Reproductive Techniques." This event aims to provide updates on genetic knowledge and clinical practice to assisted reproductive specialists.

GENTIS and Hanoi Hospital of Andrology and Infertility collaborated on research at the 15th European Society of Gynecology Symposium

On November 30th, 2023, GENTIS and Hanoi Hospital of Andrology and Infertility proudly presented their research on Preimplantation Genetic Testing for Monogenic Disorders (PGT-M) at the 15th European Society of Gynecology Conference in Amsterdam, Netherlands.

Early screening of Thalassemia - A need for couples who are both disease gene carriers.

Thalassemia is the most common monogenic genetic disorder today, causing serious consequences for the race, affecting the lives of patients and the whole community. Therefore, thalassemia testing is necessary to detect the disease gene early to help minimize treatment costs and limit the birth of suffered children.

Genetic Counseling in Assisted Reproductive Technology with Prof. Dr. Nguyen Dinh Tao and Assoc. Prof. Dr. Tran Duc Phan

On January 24, the GENTIS Genetic Counseling Center broadcasted the talk show "Genetic Counseling - Discussion with Experts" on the topic of "Genetic Counseling in Assisted Reproductive Technology (ART) - The Role of Genetic Counselors and Testing Labs" on the GENTIS fanpage. The event attracted significant attention from medical professionals working in the field of assisted reproduction, as well as from clients interested in undergoing IVF.
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