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[slug] => gentis-tham-du-hoi-nghi-ky-niem-55-nam-ngay-truyen-thong-tai-vien-mo-phoi-lam-sang-quan-doi
[title] => GENTIS tham dự Hội nghị kỷ niệm 55 năm ngày truyền thống tại Viện Mô phôi lâm sàng Quân Đội
[description] => Ngày 27/04 sắp tới, GENTIS vinh dự là nhà tài trợ đồng hành cùng Hội nghị khoa học và gặp mặt kỷ niệm 55 năm ngày truyền thống Viện Mô phôi lâm sàng Quân Đội.
[content] => Viện Mô Phôi lâm sàng Quân đội được thành lập từ ngày 27/04/1968, đến nay (27/04/2023) chính thức tròn 55 năm thành lập. Nhân kỷ niệm 55 năm truyền thống và chào đón 21 em bé đầu tiên ra đời bằng phương pháp thụ tinh trong ống nghiệm, Viện Mô phôi lâm sàng Quân Đội sẽ tổ chức Hội nghị khoa học và lễ kỷ niệm 55 năm ngày truyền thống.
Thông tin về Hội nghị:
Thời gian diễn ra: 27/04/2023.
Số lượng người tham dự: dự kiến 200 đại biểu
Địa điểm: Hội trường Đỗ Xuân Hợp - Học viện Quân Y (160 Phùng Hưng, Phúc La, Hà Đông, Hà Nội)
Hội nghị khoa học sẽ diễn ra với sự quy tụ các bài báo cáo chất lượng nhất từ các chuyên gia giàu kinh nghiệm trong nước như:
- Vô sinh và cập nhật các phác đồ kích thích buồng trứng bởi GS.Nguyễn Đình Tảo
- Viêm nội mạc tử cung mãn tính và vô sinh bởi PGS.TS Lê Hoàng
- Hạn chế của các chỉ số tinh dịch đồ trong chẩn đoán và điều trị vô sinh nam bởi PGS.TS Hồ Sỹ Hùng
- Cập nhật xu hướng về trữ lạnh noãn bởi PGS.TS Nguyễn Mạnh Hà.
Tham gia Hội nghị khoa học năm nay, GENTIS hứa hẹn sẽ mang lại cho các y bác sĩ, chuyên gia trọn bộ những kỹ thuật xét nghiệm mới nhất để ứng dụng lâm sàng trong chẩn đoán và điều trị hỗ trợ sinh sản. GENTIS xin chúc Hội nghị diễn ra thành công tốt đẹp. Cùng cập nhật thêm thông tin về Hội nghị tại Website và Fanpage GENTIS nhé!
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On the evening of April 15, the "Love Connection" golf tournament ended successfully and the awards gala was held intimately at Thanh Lanh Golf Course, Serena Valley Resort, Vinh Phuc Province. The program was honored to welcome more than 80 golfers who are politicians, businessmen, leaders of press agencies, investors of domestic and foreign construction corporations, etc. The venue is at Thanh Lanh golf course. This is one of the highlights of this tournament. The terrain of Thanh Lanh golf course is especially attractive by the undulating curves designed according to different levels of difficulty - easy, this factor has created challenges and interesting experiences for golfers.
Besides exchanging and connecting golfers to compete together, the "Love Connection" Golf tournament also has a big goal of raising charity funds for dangerous cancer children, young families in difficult circumstances. Responding to the call, joining hands to support the program, GENTIS Company sponsored more than 250 million VND including cash and health cards for the program. Established in 2010, GENTIS is the first and always a pioneer in the field of genetic analysis in Vietnam. With a diverse testing ecosystem in almost all fields of obstetrics, gynecology, and paediatrics, GENTIS has been the trusted address of more than 300,000 customers, hundreds of large hospitals across the country and other medical institutions. major companies in the world. For the mission of improving the physical and mental health of the Vietnamese people, GENTIS always strives every day to develop and improve testing services, step by step joining hands to bring happiness and smiles to every family across the country.
Charity funds raised through the program will be supported for children with cancer at K Tan Trieu Hospital, National Institute of Hematology and Blood Transfusion,... GENTIS hopes this small contribution will help them overcome through pain and illness, adding strength and fire of life to babies and families.
On that good journey, GENTIS is determined to always accompany, stand by and strengthen support with meaningful programs and activities with humanity!
With the development of modern medicine, the field of Obstetrics and Gynecology has always been an important specialty for doctors and patients. Over the years, the field of obstetrics and gynecology in Vietnam and provinces across the country has made great strides in terms of scale and level, keeping up with the development of the region and the world.
In order to update new knowledge, the first Congress of Obstetrics and Gynecology in 2023 was solemnly held by Ha Tinh Department of Health in collaboration with Ha Tinh Provincial General Hospital on the afternoon of April 8. This is a scientific forum for doctors, medical professionals, experts to exchange, learn and cultivate clinical knowledge from leading experts, thereby contributing to helping Vietnam's obstetrics and gynecology industry keep up with the development of other countries in terms of expertise and management.
The first Ha Tinh Obstetrics and Gynecology Conference attracted nearly 200 delegates with 4 papers with notable topics such as:
- Studying the effectiveness of Flare-up and Antagonist ovarian stimulation regimens on patients with poor response prognosis in IVF (Dr. Nguyen Anh Tho)
- Comments on the initial treatment of cesarean section scar cases at the Department of Obstetrics and Gynecology, Ha Tinh Province General Hospital (MSc. Nguyen Huu Nhat)
- Actual situation of cesarean section in the hospital of Ha Tinh province (BSCK2. Nguyen Co Thach)
- Evaluating the effectiveness of Nifedipine and Salbutamol in the treatment of threatened preterm labor at Ha Tinh Provincial General Hospital (Dr. Tran Chien Thang)
Delegates at the conference listened and animatedly discussed the topics of obstetrics and gynecology. In addition, many other thematic reports presented by partner units and sponsors were also of the interest of doctors and nurses at Ha Tinh Provincial General Hospital.
Prominent among them is the report of GENTIS company on Cervical cancer screening through HPV (Human Papilloma Virus) test shared by Mr. Nguyen Xuan Bach, Product Manager of GENTIS. At the conference, the representative in charge of GENTIS products raised the dangers of cervical cancer and methods to help screen the disease early to reduce the number of people infected and prevent it for Vietnamese women.
Cervical cancer is the leading cause of cancer death in 36 countries, and the leading cause of death in 23 countries. In Vietnam, cervical cancer is the second most common cancer among genital cancers in women. Every day there are about 14 new cases, including 7 deaths from cervical cancer. This is 2 to 3 times higher than deaths from complications related to pregnancy (pregnancy and childbirth).
The early symptoms of cervical cancer are vague, unclear and will usually only be detected when the disease is advanced at a late stage. However, this disease has a high chance of successful treatment if it is detected and treated properly at an early stage. Therefore, for early detection and prevention of cervical cancer, HPV-DNA testing is recommended for all women over the age of 25 who have had sex at least every 5 years (for women over 25 years of age). negative test result) to screen for cervical cancer.
The HPV-DNA test allows the detection of genetic changes in cervical cells at an early stage, and at the same time helps to assess a woman's risk of HPV infection from low to high to have an appropriate treatment plan. . Up to now, GENTIS is the unit that provides a full set of HPV tests in particular and cervical cancer screening tests in general to many hospitals, centers and clinics across the country.
By testing 40 types of HPV virus from high-risk to low-risk types, the HPV-DNA test at GENTIS has helped doctors to assess the overall health of the disease, and at the same time bring safety. heart and faith for women. As one of the early implementation units of cervical cancer testing in Vietnam, GENTIS company also conducts many counseling and guidance programs for the community to raise awareness about cervical cancer and help people. Know how to prevent and treat diseases effectively.
The report on HPV-DNA testing of GENTIS company also received the consensus of all doctors and nurses at the conference with the desire to have a large-scale screening in the community to repel cervical cancer. In addition to this report, GENTIS also gave doctors at the conference small gifts at the product display booth.
Through gifts and documents sent to doctors, GENTIS hopes to update many new tests to support doctors in the field of Obstetrics and Gynecology. Once again, GENTIS company would like to congratulate the Conference on a great success and look forward to future conferences. GENTIS promises to always ensure the quality of tests and develop many new valuable products to provide to all doctors and nurses nationwide.
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On the afternoon of April 6, GENTIS company held a conference to report on the topic "Update new information on male testing and FSH test to support ovarian stimulation treatment" at the Hospital of Andrology. Infertility Vietnam Belgium.
The seminar had the participation of more than 20 doctors and nurses from the leadership, department heads, doctors and nurses working at the Hospital, especially in the presence of Dr. BS. Le Thi Hieu - Deputy Director of the Hospital, Dr. Ha Ngoc Manh - Deputy Director of the Hospital, cum Head of the Department of Andrology.
At the exchange, BSNT. Nguyen Thi Huyen - GENTIS geneticist gave a detailed report on current gynecological tests and the latest updates at GENTIS for the Hospital side.
Through the report, the hospital's doctors had a better overview of the test indications for male patients to contribute to determining the cause of infertility, diagnosing and treating male infertility effectively. Some tests are still used for male gynecology such as: Semen map, Karyotype, AZF, sperm DNA fragmentation, CFTR... have been performed by Viet Belgium Hospital.
In addition, the GENTIS geneticist also pointed out the improvements, superiority and high quality in male testing at GENTIS that will optimally support doctors in male infertility treatment regimens.
In addition to the report on the laboratory tests, Dr. Nguyen Van Quang - GENTIS Product Manager shared about the FSH receptor gene polymorphism test, a new test developed by GENTIS to assist doctors in the process. ovarian stimulation.
The FSH receptor gene polymorphism test is a test that allows the identification of genetic variants associated with the response to ovarian stimulation. With this test, the doctor will come up with an optimal and personalized ovarian stimulation regimen for each patient. Also aids in determining the cause of poor ovarian response (POR) or in the evaluation of high-risk cases of ovarian hyperstimulation.
According to Drs. Quang, GENTIS is the first unit in the North to deploy FSH receptor gene polymorphism test and perform on 4 SNPs proven to be associated with poor ovarian response (rs6165, rs6166, rs1394205, rs10835638) .
GENTIS' FSH test report attracted the attention of many doctors at the conference. Doctor Ha Ngoc Manh (Deputy Director of the Hospital) questioned the FSH test with the recommendations for the use of drugs after the FSH test for patients with poor response to ovarian stimulation and the studies clinical research in Vietnam. This is also the goal GENTIS is conducting research on this test in Vietnam for the poor responder group to have the best comparison for doctors when ordering the test.
BS. Le Thi Hieu (Deputy Director of the Hospital) is also very interested in this test and hopes that GENTIS will research and provide the closest indication thresholds, in order to support doctors in ovarian stimulation treatment regimens. Dr. Hieu said that in the coming time, Viet Belgium Hospital will also offer plans to support GENTIS in research on FSH testing.
After the discussion, GENTIS and the Vietnam - Belgium Hospital of Andrology & Infertility have come up with many useful cooperation proposals to apply high-tech tests in clinical practice, helping infertility treatment cases more effective to saving time and costs.
Once again, congratulations on the successful seminar and will continue to deploy more useful exchanges to hospitals across the country.
Following the success of a series of seminars organized by the Hanoi Society for Assisted Reproductive Medicine (HTSS), this ART Advance 08 knowledge exchange forum with the theme "The Art of Trait-Based Assisted Reproductive Therapy" patients” has attracted more than 250 leading experts and medical staff in the field of assisted reproductive technology. Under the chairmanship and management of Prof. TS.BS Nguyen Dinh Tao - Chairman of Hanoi HTSS Association, the workshop took place with 2 working sessions and 8 papers presented and discussed by experts. leading healthcare provider in the field of assisted reproduction and genetic testing in Vietnam.
In the morning session at the Workshop, Assoc. Prof. Dr. Nguyen Thanh Tung shared on the topic "Combining culture genetic analysis and embryo morphology in screening and evaluating embryo quality". Associate Professor Tung said that there are currently many studies proving the scientific and clinical basis of genetic screening tests before embryo transfer based on the embryo culture environment.
The assay for analyzing embryo culture is under intense research and development, providing an additional basis for genetic screening for embryos. The process of culturing and collecting culture samples for niPGT-A test plays a very important role, greatly affecting the test results, especially the removal of cells of maternal origin. Currently, GENTIS is the only pioneer in providing analytical testing of embryo culture medium (ASEM Test) with outstanding advantages such as:
• Provide information on chromosomal genetic status through analysis of embryo culture environment, combined with embryo morphological assessment to select transfer/storage embryos.
• Limiting invasive manipulations to the embryo helps to reduce concerns about the effect of biopsy on the embryo.
Next, Assoc. Prof. TS.BS Ho Sy Hung also had a report on "Mosaic embryo transfer: Updated guidelines and treatment". Associate Professor Ho Sy Hung shared: “The results of the mosaic embryos are part of the PGT-A results. According to the International Consortium for Preimplantation Genetic Diagnosis (PGDIS) 2021, embryos with high mosaicism may have an increased risk of adverse clinical outcomes compared with embryos with low mosaicism (limited data)
If the two embryos have similar mosaicism, then we will consider embryo selection based on embryo morphology, then consider the type of abnormality (preference is given to embryos with total chromosomal mosaicism, then partial chromosomal abnormalities, then partial chromosomal mosaicism)
In summary, mosaic embryo transfer has less effective clinical outcomes than haploid embryo transfer. We will always prioritize haploid embryo transfer and consider mosaic embryo transfer when there are no or no more normal embryos to transfer. If we have to decide to transfer mosaic embryos, we will choose embryos to transfer according to the following parameters: Embryos with low mosaicism, mosaic chromosomes (as recommended) and mosaic type.
PGT-A is one of the preimplantation genetic tests to help detect aneuploidy of 24 pairs of chromosomes and abnormality of chromosome structure at GENTIS, in case when the patient chooses to perform mosaic embryo transfer, the patient will be fully consulted by clinical geneticists regarding PGT-A results and possible clinical outcomes. The decision to transfer mosaic embryos will be made after careful consideration of the benefits, risks, and alternatives.
In addition, there is a report by Assoc. Prof. TS.BS Nguyen Quang on "Expanding the audience using the Sperm fragmentation test". Sperm fragmentation (PMTT) is damage to one or both strands of the DNA molecule in sperm, causing the DNA strand to split or break into small pieces. When the genetic integrity of sperm is affected, it results in effects on male fertility and is greatly related to reproductive planning.
SPossessing a complete set of tests in the field of male, GENTIS sperm fragmentation test uses SCSA method (the method is considered the gold standard in sperm DNA fragmentation assessment with high accuracy, process simple implementation, quick response time) direct quantification of sperm DNA fragmentation through Flow cytometry based on dye discoloration. It can be said that PMTT test is a very important test in determining the degree of sperm DNA fragmentation to find the cause of male infertility.
At the end of the morning session, Dr. Pham Dinh Minh - R&D Director of GENTIS Company had a detailed presentation through the report "Some new advances in PGT preimplantation genetic testing by new generation gene sequencing technology "NGS".
TThe afternoon session opened with the report "The role of FSH receptor gene analysis in the individualization of the stimulation dDr. Minh said: “Currently, GENTIS Company has had new approaches and breakthroughs in the treatment of infertility through the latest tests such as PGT MAX 1 test (high resolution PGT test, with outstanding advantages can detect additional microdeletions as small as 2Mb, associated with dangerous syndromes such as 1p36 and DiGeorge); One PGT-M test (is a PGT-M test combined with a PGT-A test, developed for common single-cell recessive diseases. The One PGT-M test uses 300-500 markers. SNP for linkage genetic analysis,...)".
Prof. TS.BS Nguyen Xuan Hoi, which received much attention and appreciation from many people. PGS Hoi said that FSH receptor gene polymorphism test combined with other indicators (AMH, AFC, maternal age ...) is very helpful for doctors to personalize the ovulation regimen.
At GENTIS, testing for FSH receptor gene polymorphisms on 4 SNPs that have been shown to be associated with poor ovarian response is rs6165, rs6166, rs1394205, rs10835638. With only 2-3ml of whole blood sample stored in EDTA anticoagulant tube, using Sanger and NGS sequencing techniques on Miseq/Nextseq sequencer system and capillary electrophoresis machine, receptor gene polymorphism test GENTIS FSH will help the physician to come up with the most optimal and personalized ovarian stimulation regimen for each patient, helping to find the cause of poor ovarian response (POR). In the future, GENTIS will continue to research and optimize the gene polymorphisms related to ovarian hyperstimulation.
The seminar was lively, many questions were raised and discussed in the discussion section to help doctors gather more knowledge, get closer to methods as well as new perspectives on treatment. infertility in the world.
In addition to the reports within the conference framework, at the product display booth, GENTIS also had many other interesting gameshow activities with countless attractive gifts awarded. Here, doctors and specialists will be introduced to the latest testing services and consult the book "Male Infertility under the lens of genetics" compiled and published exclusively by GENTIS.
At the end of the seminar, Prof. TS.BS Nguyen Dinh Tao thanked the sponsors for accompanying the program and delegates from all over the country who attended the ART Advanced 08 scientific forum. Prof. TS.BS Nguyen Dinh Tao said that individualization of treatment is the use of treatment measures suitable to the pathological characteristics of each individual patient, the personalized strategy of treatment should be the standard clinical practice in assisted reproduction. That is, based on the "genomic map" of each person, we will use complex and delicate diagnoses to come up with an accurate treatment plan, suitable for each person's genetic characteristics, towards more effective treatment with fewer side effects. Therefore, individualizing the treatment to maximize the chances of success is essential and important!
GENTIS will also always strive to develop to bring the most advanced and safest testing technical solutions for the purpose of improving the physical and intellectual capacity of Vietnamese people. Once again, GENTIS would like to congratulate the ART Advanced Science Forum 08 on a great success and bringing useful knowledge to doctors and nurses across the country.
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After 44 years of development in the world and 24 years of development in Vietnam, the Assisted Reproductive Industry plays an increasingly important role and has achieved remarkable successes in supporting infertile couples to have a association of being a parent. However, despite great scientific advances, the success rate of many couples is still not as desired.
Vietnam is one of the countries with a strong growth rate in terms of quantity and quality of infertility treatment. In order to improve the quality of treatment, scientists have constantly updated knowledge, scientific and technical advances and continued to share experiences in IVF.
Following the success of 2022, the Hanoi Society for Assisted Reproductive Medicine will organize the ART Advanced 08 Knowledge Exchange Forum with the theme "Art of assisted reproductive treatment based on patient characteristics".
This is a particularly attractive seminar with the gathering of the best quality reports from experienced domestic and foreign experts.
Information about the Conference:
Time to take place: April 1, 2023.
Number of attendees: expected 200 delegates
Delegates: Executive Board of Hanoi Fertility Support Association, Head of Lab, clinicians, embryologists and leaders of leading Reproductive Support Centers in 3 North, Central and South regions.
Location: Meliá Hanoi Hotel, 44 Ly Thuong Kiet, Hoan Kiem, City. Hanoi
Main content:
Participating in this year's Forum, GENTIS promises to bring doctors and experts a complete set of the latest testing techniques for clinical application in diagnosis and assisted reproductive treatment based on disease characteristics. core. GENTIS would like to wish the Conference a great success. Let's update more information about the Conference at GENTIS Website and Fanpage!
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PGT testing can be divided into 3 groups according to specific purposes when genetic testing of embryos as follows:
+ PGT-A (Preimplantation Genetic Screening for Aneuploidy): Pre-implantation genetic testing helps to detect abnormalities in the chromosome number of embryos before transferring into the mother's uterus.
+ PGT-SR (Preimplantation genetic testing for structural chromosomal rearrangements): Pre-implantation genetic testing helps to detect structural chromosomal abnormalities.
+ PGT-M (Preimplantation genetic testing for monogenic/single gene defects): is a pre-implantation genetic test for single-gene diseases, indicated as embryos for couples carrying known genetic abnormalities. examines and detects embryo-specific single-gene mutations. PGT-M embryos without genetic disease will be prioritized to be transferred to the mother's uterus to eliminate single-gene genetic disease for the next generation.
Previously, PGT-M was called PGD (pre-implantation genetic diagnosis) and PGT-A was called PGS (known as preimplantation genetic screening). These two tests, when combined, can greatly improve your chances of a healthy pregnancy.
What does the PGT . test mean?
The PGT provides information about the genetic health of the embryo to help fertility professionals select the best embryos, and it also helps:
• Increase your chances of getting pregnant
• Reduce the risk of miscarriage
• More confidence when transferring single embryos, avoiding health risks when having to transplant double or triple embryos.
• Reducing the number of IVF cycles needed to conceive, which can reduce the time it takes for a successful pregnancy as well as the cost of each additional IVF session.
• Increase your chances of having a healthy baby
Who is the PGT assigned to?
1. PGT-M:
- Husband and wife carry genetic mutations that cause diseases such as Thalassemia, Myelodystrophy, ...
- Wife carries X-linked gene mutation (Hemophilia, Duchenne/Becker muscular dystrophy...)
2. PGT-SR:
- Spouse carries abnormal chromosomal structure: balanced chromosomal translocation, chromosomal deletion or duplication...
3. PGT-A:
- Miscarriage 3 times in a row
- Older wife (≥ 36 years old)
- IVF failed multiple times (≥ 3 times)
- Husband is severely infertile (loss of AZF segment)
How is PGT done?
When a PGT test is indicated:
- • The specialist performing the PGT will perform an embryo biopsy on day 3 (1 cell) or day 5 (5 to 10 blastocyst cells) to be sent for genetic testing.
• Embryos after biopsy will be frozen and ensure the principle of freezing 1 embryo / storage device.
• The embryonic cell sample after biopsy will be sent to the genetics laboratory for analysis.
• The couple will be consulted by the treating doctor about the usability of the embryos based on the genetic test results and are committed to keeping the results confidential.
• Endometrial preparation, frozen embryo transfer and pregnancy testing were performed as usual.
• The process of monitoring the pregnancy in the future still has to be done regularly under the advice of a specialist like other pregnancies.
Currently, PGT tests can be performed at some specialized hospitals or assisted reproductive centers in Vietnam, however GENTIS is one of the few pioneers, capable of performing the test. Precise and professional pre-implantation experience with the most modern advanced technical technology and a team of senior experts. Through the PGT test, GENTIS wishes to bring healthy babies and bring happiness to families across the country.
[content_more] => [meta_title] => Distinguish 3 groups of commonly used PGT tests [meta_description] => Preimplantation Genetic Testing (PGT) is a specialized technique to identify genetic abnormalities of embryos produced by in vitro fertilization (IVF/ICSI). [meta_keyword] => gentis,pgtest [thumbnail_alt] => [post_id] => 1073 [category_id] => 4 ) [7] => stdClass Object ( [id] => 1072 [id_crawler] => [category_product] => NULL [thumbnail] => bao_cao_tai_bv/san_nhi_phu_tho/logo-1.jpg [album] => [url_video] => [is_status] => 1 [is_featured] => 0 [is_form] => 0 [displayed_time] => 2023-03-17 [program] => 0 [number] => 1 [viewed] => 0 [type] => [type_career] => [level] => [address] => [address_career] => [expiration_time] => 0000-00-00 [created_time] => 2023-03-25 10:42:50 [updated_time] => 2023-08-23 10:56:52 [files] => [salary] => [time] => [created_by] => 63 [is_table_content] => 0 [language_code] => en [slug] => gentis-cap-nhat-toi-uu-moi-ve-ky-thuat-pgtm-tai-bv-san-nhi-phu-tho [title] => GENTIS updates new optimization on PGT-M technique at Phu Tho Obstetrics and Gynecology Hospital [description] => On March 16, GENTIS company held a seminar to update new information on genetic analysis techniques before transferring PGT-M single-gene disease embryos to the team of doctors at the Fertility Support Dept of Phu Tho Obstetrics and Pediatrics Hospital. [content] =>
Following the series of activities to update knowledge about genetic analysis and testing services of GENTIS, the company organized a presentation seminar on the topic " Optimization of the PGT-M assay in preimplantation genetic analysis" at Phu Tho Obstetrics and Pediatrics Hospital on March 16.
The seminar was attended by nearly 20 doctors and nurses from the leadership of the Center for Reproductive Support and Male Studies of the Hospital. In particular, there was the presence of Dr. Doctor Doan Xuan Kien - Director of Center for Reproductive Support, MSc. Dr. Nguyen Thi Mai - Deputy Director of Center for Reproductive Support and doctors, nurses and technicians working at the central laboratory. GENTIS Company is honored to have the participation of Drs. Duong Thi Phuong - GENTIS Product Management Team Leader directly reports on the latest updates on the PGT-M test.
At the beginning of the report, Pharmacist Phuong shared preliminary about genetic analysis test before embryo transfer. In which, the GENTIS Product Management Team Leader focused on reporting on PGT-M to identify monogenic genetic diseases and its applicability to infertile couples with monogenic genetic diseases.
According to world statistics, the prevalence of monogenic diseases accounts for about 3.5-5.9% of the world population (>400 million patients). Some common single-gene diseases such as Thalassemia, spinal muscular atrophy, Duchenne muscular atrophy, hemophilia, etc. have caused dangerous genetic consequences for many generations of families.
With the development of world science, the PGT-M technique was born, helping many couples with single-gene genetic diseases have a chance to have healthy children. PGT-M is a test performed on embryos, to detect inherited diseases caused by pre-defined gene mutations or with a clear family history.
GENTIS is the unit that has deployed PGT-M at many fertility centers across the country and received very good feedback on the quality of implementation. Dr. Phuong shared that the PGT-M test at GENTIS has been performed with more than 30 genetic disease syndromes. Not only are common single-gene diseases detected, but other rare and dangerous genetic diseases are also performed by GENTIS experts such as Wilson's disease, Pompe syndrome, cystic fibrosis, Fabry disease, congenital hearing loss. , congenital hypothyroidism, Smith-Lemli-Opitz syndrome, vitreous bone disease, inherited polycystic kidney ...
From there, Dr. Duong Thi Phuong emphasized the information that GENTIS successfully optimized the PGT-M test kit including 10 dangerous single-gene diseases, helping to shorten the time to return results from 60 days to only 30 days.
The procedure for performing this test consists of collecting a biopsy embryo or WGA product, along with a reference blood sample from the parents. In some cases, GENTIS may require a third or additional reference sample for the most accurate and clear mutation identification.
In addition to the diseases on the implementation list, the Product Management Team Leader said that GENTIS can perform PGT-M for most diseases and genes, including new diseases that have not yet been implemented in Vietnam. This is one of the great advantages that not all testing units in Vietnam can do.
Besides PGT genetic testing for embryos, parental target gene testing is also an important test for people with a history of genetic diseases or suspected monogenic diseases. Patients will receive counseling and guidance on common monogenic disease screening by GENTIS geneticists.
At that time, the patient can perform the GENTIS 13 hidden genetic disease test package to simultaneously detect mutations in genes related to 13 common genetic diseases in Asians. This is a useful tool to help each individual check whether he or she carries the disease gene or not and assess the possibility of passing the disease gene to children.
At the end of the seminar, doctors at Phu Tho Obstetrics and Pediatrics Hospital had a lively discussion with GENTIS representatives about sample preservation, sample collection as well as the process of performing PGT-M test to detect disease. Thalassemia. According to the Deputy Director of the Center - Mr. Dr. Nguyen Thi Mai, the hospital is currently accepting many patients with problems related to Thalassemia who want to have a healthy baby. The doctor also said that this disease is very dangerous and it is necessary to be screened to limit the birth of sick children and reduce the burden on the family and society.
After an exchange with a representative of Phu Tho Obstetrics and Gynecology Hospital, the GENTIS representative presented the effectiveness of using the PGT-M test in Thalassemia screening and applying it in more than 50 birth reproductive support centers nationwide. GENTIS is committed to implementing rigorous and ISO 9001:2015 PGT-M testing procedures to ensure accurate and reliable results in the shortest possible time.
With the desire to share knowledge about PGT technique and methods to support people with genetic diseases to have healthy children, GENTIS hopes that doctors at Phu Tho Obstetrics and Pediatrics Hospital have had more useful information to advise and consultation with the patient. The company will continue to research on PGT-M on many other rare genetic diseases, increase the success rate for pre-implantation screening and bring happiness to families in Vietnam..
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Distinguish 3 groups of commonly used PGT tests
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